CAS 305346-88-7

1-(2-Methylpropyl)-1H-benzimidazole

Description:

1-(2-Methylpropyl)-1H-benzimidazole, identified by its CAS number 305346-88-7, is a chemical compound that belongs to the class of benzimidazoles, which are characterized by a fused benzene and imidazole ring structure. This compound features a 2-methylpropyl group attached to the nitrogen of the benzimidazole ring, influencing its physical and chemical properties. Typically, benzimidazoles exhibit a range of biological activities, including antifungal, antiviral, and anticancer properties, making them of interest in pharmaceutical research. The presence of the alkyl substituent can enhance lipophilicity, potentially affecting the compound's solubility and permeability. In terms of physical properties, benzimidazoles generally have moderate melting points and may be crystalline solids at room temperature. The compound's reactivity can be influenced by the functional groups present, allowing for various chemical transformations. Overall, 1-(2-Methylpropyl)-1H-benzimidazole represents a versatile structure with potential applications in medicinal chemistry and material science.

Formula: C₁₁H₁₄N₂

InChI: InChI=1S/C11H14N2/c1-9(2)7-13-8-12-10-5-3-4-6-11(10)13/h3-6,8-9H,7H2,1-2H3

InChI key: InChIKey=VZDLNMJLPUIVIN-UHFFFAOYSA-N

SMILES: C(C(C)C)N1C=2C(N=C1)=CC=CC2

Synonyms:

• 1-(2-Methylpropyl)-1H-1,3-benzodiazole
• 1-(2-Methylpropyl)-1H-benzimidazole
• 1-Isobutyl-1H-benzimidazole
• 1-Isobutylbenzimidazole
• 1H-Benzimidazole,1-(2-methylpropyl)-(9CI)
• 1H-Benzimidazole, 1-(2-methylpropyl)-

1-Isobutyl-1H-benzimidazole

CAS: 305346-88-7

1-Isobutyl-1H-benzimidazole

Formula: C₁₁H₁₄N₂

Purity: ≥95%

Color and Shape: off-white powder

Molecular weight: 174.24226g/mol

Ref: 54-OR2267

1-Isobutyl-1H-benzimidazole

CAS: 305346-88-7

1-Isobutyl-1H-benzimidazole is a potent and selective inhibitor of cell proliferation. It inhibits the growth of cancer cells by targeting the catalytic activity of topoisomerase II. The in vitro cytotoxic activity of 1-isobutyl-1H-benzimidazole has been investigated on human cancer cells and endometrial cancer cells. The IC50 values for cisplatin, a chemotherapeutic agent, and 1-isobutyl-1H-benzimidazole were found to be identical at 10 μM. Endometrial cancer cells were more sensitive to 1-isobutyl-1H-benzimidazole than human cancer cells.

Formula: C₁₁H₁₄N₂

Purity: Min. 95%

Molecular weight: 174.24 g/mol

Ref: 3D-FMA34688