CAS 3053537-06-4

RD-23

CAS: 3053537-06-4

RD-23 is an orally active and selective RET PROTAC degrader. It facilitates the ubiquitination and degradation of the RETG810C mutant with a DC50 value of 11.7 nM. Additionally, RD-23 inhibits the activation of downstream Shc signaling and induces apoptosis (Apoptosis). It is useful for studying RET-related cancers.

Formula: C₅₂H₅₆N₁₂O₄

Color and Shape: Solid

Molecular weight: 913.079

Ref: TM-T204442