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CAS 3053537-06-4

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  • RD-23

    CAS:
    <p>RD-23 is an orally active and selective RET PROTAC degrader. It facilitates the ubiquitination and degradation of the RETG810C mutant with a DC50 value of 11.7 nM. Additionally, RD-23 inhibits the activation of downstream Shc signaling and induces apoptosis (Apoptosis). It is useful for studying RET-related cancers.</p>
    Formula:C52H56N12O4
    Color and Shape:Solid
    Molecular weight:913.079