CAS 3053753-61-7

1,5-Naphthyridin-4-amine, 6-(6-methoxy-3-pyridinyl)-N-(3R)-3-pyrrolidinyl-

Description:

1,5-Naphthyridin-4-amine, 6-(6-methoxy-3-pyridinyl)-N-(3R)-3-pyrrolidinyl- is a chemical compound characterized by its complex structure, which includes a naphthyridine core, an amine functional group, and a pyrrolidine moiety. This compound is likely to exhibit properties typical of heterocyclic amines, such as potential basicity due to the presence of nitrogen atoms in its structure. The methoxy and pyridinyl substituents may contribute to its solubility and reactivity, influencing its interaction with biological targets. Compounds of this nature are often investigated for their pharmacological properties, including potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. The presence of multiple nitrogen atoms suggests that it may engage in hydrogen bonding and other interactions, which can be crucial for its biological activity. Overall, this compound's unique structural features may render it of interest in various fields, including drug discovery and materials science.

Formula: C₁₈H₁₉N₅O

Synonyms:

• 1,5-Naphthyridin-4-amine, 6-(6-methoxy-3-pyridinyl)-N-(3R)-3-pyrrolidinyl-

SARS-CoV-2 PLpro-IN-1

CAS: 3053753-61-7

SARS-CoV-2 PLpro-IN-1 (Compound 85) is a non-covalent competitive inhibitor of SARS-CoV-2 PLpro with an IC50 value of 15.06 μM and a Ki value of 22.93 μM. It inhibits the proliferation of Vero cells, exhibiting an IC50 of 7.47 μM.

Formula: C₁₈H₁₉N₅O

Color and Shape: Solid

Molecular weight: 321.376

Ref: TM-T204451