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CAS 3054043-85-2

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  • PD-L1/Nampt-IN-1
    Targetmol
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    PD-L1/Nampt-IN-1

    CAS:
    PD-L1/Nampt-IN-1 is an orally active inhibitor that targets both PD-L1 and NAMPT (nicotinamide phosphoribosyltransferase), with IC50 values of 63 nM and 582 nM, respectively. It exhibits cross-species affinity, with KD values of 52.6 nM for hPD-L1 and 49.1 nM for mPD-L1. This compound effectively suppresses tumor growth by activating the tumor immune microenvironment and is applicable in melanoma research.
    Formula:C28H28N4O2
    Color and Shape:Solid
    Molecular weight:452.55

    Ref: TM-T212272