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CAS 3055107-34-8

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  • BT-O2C

    CAS:
    BT-O2C is a highly selective p300 PROTAC degrader that effectively reduces p300 levels in HAP1 cells. It exhibits significant cytotoxicity in CIC:DUX4 sarcoma (CDS) cell lines, with an IC50 of 152-221 nM, and notably decreases the expression of CDS target genes (ETV1, ETV4, ETV5). BT-O2C is applicable in cancer research.
    Formula:C48H48F5N9O8
    Color and Shape:Solid
    Molecular weight:973.94

    Ref: TM-T210582

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