CAS 3055471-57-0

1-Piperazineacetamide, 4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-N-[7-[[3-[[[6-(dimethylamino)-3-pyridazinyl]amino]carbonyl]-6-(methylamino)-2-pyridinyl]amino]heptyl]-

Description:

1-Piperazineacetamide, 4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-N-[7-[[3-[[[6-(dimethylamino)-3-pyridazinyl]amino]carbonyl]-6-(methylamino)-2-pyridinyl]amino]heptyl]- is a complex organic compound characterized by its multi-ring structure and various functional groups, including piperazine and pyrimidine moieties. This compound exhibits potential pharmacological properties, often explored in medicinal chemistry for its possible therapeutic applications. Its intricate structure suggests it may interact with biological targets, potentially influencing various biochemical pathways. The presence of multiple nitrogen atoms in the piperazine and pyrimidine rings may contribute to its solubility and reactivity, while the acetyl and dimethylamino groups could enhance its biological activity. As a synthetic compound, it is typically studied for its efficacy and safety in drug development, with a focus on optimizing its pharmacokinetic and pharmacodynamic profiles. Further research is necessary to fully elucidate its mechanisms of action and potential therapeutic benefits.

Formula: C₄₆H₆₁N₁₅O₄

Synonyms:

• 1-Piperazineacetamide, 4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-N-[7-[[3-[[[6-(dimethylamino)-3-pyridazinyl]amino]carbonyl]-6-(methylamino)-2-pyridinyl]amino]heptyl]-

CPD-10

CAS: 3055471-57-0

CPD-10 is a potent bifunctional PROTAC degrader targeting CCND1 and CDK4 and exhibits antiproliferative effects. It induces apoptosis and reduces the protein expression of Cyclin D1, Cyclin D3, CDK4, and P-Rb(5807/811) in a dose-dependent manner.

Formula: C₄₆H₆₁N₁₅O₄

Color and Shape: Solid

Molecular weight: 888.08

Ref: TM-T201577