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CAS 3057176-00-5

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  • EP-3945
    Targetmol
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    EP-3945

    CAS:
    <p>EP-3945 is an agonist of Mas-related G protein-coupled receptors (MRGPR), exhibiting greater potency than the small molecule agonist β-Alanine targeting MRGPRD. MRGPRs play a crucial role in inflammatory itch and pain perception. These receptors interact with Gq (MRGPRX2, MRGPRX4, and MRGPRX1 are coupled with Gq; MRGPRX2 and MRGPRD couple with Gi), with EP-3945 having an EC50 value of 211.6 nM for Gq.</p>
    Formula:C24H26N4O3
    Color and Shape:Solid
    Molecular weight:418.488

    Ref: TM-T205219