CAS 30578-37-1

Amezinium metilsulfate

Description:

Amezinium methylsulfate is a quaternary ammonium compound that serves primarily as a pharmacological agent. It is characterized by its role as a neuromuscular blocking agent, often utilized in clinical settings to facilitate surgical procedures by inducing muscle relaxation. The compound is typically presented as a white crystalline powder, soluble in water, which allows for easy administration in medical applications. Amezinium methylsulfate acts by blocking the transmission of nerve impulses to muscles, thereby inhibiting muscle contraction. Its pharmacodynamics involve competitive antagonism at the neuromuscular junction, which is crucial for its effectiveness in anesthesia. Additionally, the compound's stability and solubility make it suitable for intravenous use. Safety and efficacy profiles are essential considerations in its application, and it is subject to regulatory oversight to ensure proper usage in medical contexts. As with many pharmacological agents, potential side effects and contraindications must be carefully monitored during its use.

Formula: C₁₁H₁₂N₃O·CH₃O₄S

InChI: InChI=1S/C11H11N3O.CH4O4S/c1-15-11-7-9(12)8-13-14(11)10-5-3-2-4-6-10;1-5-6(2,3)4/h2-8,12H,1H3;1H3,(H,2,3,4)

InChI key: InChIKey=ZEASXVYVFFXULL-UHFFFAOYSA-N

SMILES: O(C)C=1[N+](=NC=C(N)C1)C2=CC=CC=C2.S(OC)(=O)(=O)[O-]

Synonyms:

• 1-Phenyl-4-amino-6-methoxypyridazinium methyl sulfate
• 30578-37-1
• 4-Amino-6-Methoxy-1-Phenylpyridazin-1-Ium Methyl Sulfate
• Amezinium Methylsulfate
• Amezinium methyl sulfate
• Amezinium metilsulfate
• Lu 1631
• Pyridazinium, 4-amino-6-methoxy-1-phenyl-, methyl sulfate
• Pyridazinium, 4-amino-6-methoxy-1-phenyl-, methyl sulfate (1:1)
• Regulton
• Risumic

Pyridazinium, 4-amino-6-methoxy-1-phenyl-, methyl sulfate

CAS: 30578-37-1

Formula: C₁₂H₁₅N₃O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 313.3296

Ref: IN-DA00I5QP

Amezinium methylsulfate

CAS: 30578-37-1

Amezinium methylsulfate

Purity: ≥98%

Molecular weight: 313.33g/mol

Ref: 54-BUP16587

Amezinium Methyl Sulfate

CAS: 30578-37-1

Amezinium Methyl Sulfate

Purity: 98%

Molecular weight: 313.33g/mol

Ref: 54-OR1023404

Amezinium Methyl Sulfate

CAS: 30578-37-1

Formula: C₁₂H₁₅N₃O₅S

Purity: >98.0%(HPLC)(qNMR)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 313.33

Ref: 3B-A2425

Amezinium methylsulfate

CAS: 30578-37-1

Amezinium methylsulfate (Lu-1631) has multiple mechanisms, including stimulation of α and β-1 receptors and inhibition of noradrenaline and tyramine uptake.

Formula: C₁₂H₁₅N₃O₅S

Purity: 99.64%

Color and Shape: Solid

Molecular weight: 313.33

Ref: TM-T5327

Amezinium methyl sulfate

CAS: 30578-37-1

Amezinium methyl sulfate is a drug that is used to treat congestive heart failure. It inhibits the enzyme renin, which is needed for angiotensin II formation. Amezinium methyl sulfate also reduces the production of natriuretic peptides and lowers blood pressure. This drug has been shown to be effective in treating diabetic neuropathy, but has not been studied extensively in this area. Amezinium methyl sulfate can be administered by intravenous or intra-arterial routes and requires a sample preparation before administration. The half-life of amezinium methyl sulfate is 3 hours and it is metabolized through glucuronidation.

Formula: C₁₂H₁₅N₃O₅S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 313.33 g/mol

Ref: 3D-FA29468

4-Amino-6-methoxy-1-phenylpyridazin-1-ium methyl sulfate

CAS: 30578-37-1

Formula: C₁₂H₁₅N₃O₅S

Purity: 98%

Molecular weight: 313.33

Ref: 10-F516420