CAS 305820-75-1

Pyrido[2,3-d]pyrimidin-7(8H)-one,6-(2,6-dichlorophenyl)-8-methyl-2-[[4-(4-morpholinyl)phenyl]amino]-

Description:

Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2,6-dichlorophenyl)-8-methyl-2-[[4-(4-morpholinyl)phenyl]amino]- is a complex organic compound characterized by its fused pyrido and pyrimidine rings, which contribute to its heterocyclic nature. The presence of a dichlorophenyl group and a morpholinyl-substituted phenyl moiety enhances its potential for biological activity, making it of interest in medicinal chemistry. This compound typically exhibits moderate to high lipophilicity due to its aromatic and halogenated structures, which can influence its solubility and permeability in biological systems. Its molecular structure suggests potential interactions with various biological targets, possibly acting as an inhibitor or modulator in specific pathways. The compound's unique arrangement of functional groups may also impart specific pharmacokinetic properties, such as metabolic stability and bioavailability. Overall, this substance represents a class of compounds that may have applications in drug development, particularly in the fields of oncology or neurology, although specific biological activities would require empirical investigation.

Formula: C₂₄H₂₁Cl₂N₅O₂

PD173952

CAS: 305820-75-1

Formula: C₂₄H₂₁Cl₂N₅O₂

Molecular weight: 482.36

Ref: 7W-GL2056

PD173952

CAS: 305820-75-1

PD173952

Purity: ≥98%

Molecular weight: 482.36g/mol

Ref: 54-BUP01008

PD-173952

Controlled Product

CAS: 305820-75-1

Applications PD-173952 is a Bcr-Abl tyrosine kinase inhibitor used in treatment research for chronic myelegenous leukemia (CML).
References Dorsey, J.F. et al.: Leukemia, 16, 1589 (2002); Wisniewski, D. et al.: Canc. Res., 62, 4244 (2002); Mizenina, O.A. et al.: Cell Cycle, 3, 796 (2004);

Formula: C₂₄H₂₁Cl₂N₅O₂

Color and Shape: Neat

Molecular weight: 482.36

Ref: TR-P217800

PD 173952

CAS: 305820-75-1

Inhibitor of SRC-family of kinases

Formula: C₂₄H₂₁Cl₂N₅O₂

Purity: Min. 95%

Molecular weight: 482.36 g/mol

Ref: 3D-FP26778

PD173952

CAS: 305820-75-1

PD173952 is a Src kinase and Myt1 inhibitor with antitumor activity, inhibits Lyn, Abl and Csk, and induces Bcr-Abl-dependent hematopoietic cell apoptosis.

Formula: C₂₄H₂₁Cl₂N₅O₂

Purity: 99.5%

Color and Shape: Solid

Molecular weight: 482.36

Ref: TM-T24602