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CAS 305833-60-7

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tetracycline hydrate

Description:
Tetracycline hydrate, with the CAS number 305833-60-7, is a broad-spectrum antibiotic belonging to the tetracycline class of antibiotics. It is characterized by its ability to inhibit bacterial protein synthesis, making it effective against a wide range of gram-positive and gram-negative bacteria. The substance is typically presented as a yellowish crystalline powder that is soluble in water, which is essential for its bioavailability when administered. Tetracycline hydrate is often used in both human and veterinary medicine to treat various infections, including respiratory tract infections, urinary tract infections, and acne. Its mechanism of action involves binding to the 30S ribosomal subunit of bacteria, preventing the attachment of aminoacyl-tRNA and thus inhibiting protein synthesis. However, the use of tetracycline is associated with certain side effects, including gastrointestinal disturbances and photosensitivity. Additionally, due to the potential for antibiotic resistance, its use is often guided by susceptibility testing. Proper storage conditions are crucial to maintain its stability and efficacy.
Formula:C22H26N2O9
InChI:InChI=1/C22H24N2O8.H2O/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,30-32H,7,23H2,1-3H3;1H2/b20-14+;/t9?,10-,15-,21+,22-;/m0./s1
Synonyms:
  • (2E,4S,4aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrate
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