CAS 306-07-0

Pargyline hydrochloride

Description:

Pargyline hydrochloride is a pharmaceutical compound primarily recognized for its role as a monoamine oxidase inhibitor (MAOI). It is commonly used in the treatment of certain types of depression and has been investigated for its neuroprotective properties. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Pargyline acts by inhibiting the enzyme monoamine oxidase, thereby increasing the levels of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain, which can help alleviate depressive symptoms. Its chemical structure includes a pyridine ring, contributing to its pharmacological activity. While effective, the use of pargyline hydrochloride requires careful monitoring due to potential dietary restrictions and interactions with other medications, particularly those containing tyramine, which can lead to hypertensive crises. As with any MAOI, patients must be informed about the risks and benefits associated with its use.

Formula: C₁₁H₁₄ClN

InChI: InChI=1/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H

InChI key: InChIKey=BCXCABRDBBWWGY-UHFFFAOYSA-N

SMILES: C(N(CC#C)C)C1=CC=CC=C1.Cl

Synonyms:

• A 19120
• Benzenemethanamine, N-methyl-N-2-propyn-1-yl-, hydrochloride (1:1)
• Benzenemethanamine, N-methyl-N-2-propynyl-, hydrochloride
• Benzylamine, N-methyl-N-2-propynyl-, hydrochloride
• Eutonyl
• Eutonyl-ten
• Methylbenzylpropynylamine hydrochloride
• Mo 911
• N-Benzyl-N-methyl-2-propynylamine hydrochloride
• N-Methyl-N-(2-propynyl)benzylamine hydrochloride
• N-Methyl-N-2-propynylbenzylamine hydrochloride
• N-benzyl-N-methylprop-2-yn-1-amine
• N-benzyl-N-methylprop-2-yn-1-amine hydrochloride (1:1)
• N-methyl-N-propargylbenzylamine hydro-chloride
• NSC 43798
• Parguline HCL
• Pargyline Hcl
• n-methyl-n-2-propynyl-benzylaminhydrochloride
• PARGYLINE HYDROCHLOR
• PARGYLINE HYDROCHLORIDE MAO INHIBITOR
• N-METHYL-N-PROPARGYLBENZYLAMINE HYDROCHLORIDE
• benzylmethylpropynylaminehydrochloride
• N-methyl-N-(phenylmethyl)-2-propyn-1-amine hydrochloride
• n-benzyl-n-methyl-2-propynylaminhydrochloride
• N-Methyl-npropargylbenzeneMethanaMine HCl
• n-benzyl-n-methyl-2-propynylaminehydrochloride
• N-METHYL-N-(2-PROPYNY)BENZYLAMINE HYDROCHLORIDE
• N-benzyl-N-methylprop-2-yn-1-amine hydrochloride
• N-methyl-N-(phenylmethyl)prop-2-yn-1-amine hydrochloride
• Pargyline Hydrochloride (200 mg)
• PARGYLINE HYDROCHLORIDE USP/EP/BP
• PARGYLINE HYDROCHLORIDE
• pargylinechloride
• benzyl-methyl-propargyl-amine hydrochloride
• N-Methyl-N-(2-propynyl)benzylamine hydrochloride, N-Methyl-N-propargylbenzylamine hydrochloride
• Pargyline hydrochloride,N-Methyl-N-(2-propynyl)benzylamine hydrochloride, N-Methyl-N-propargylbenzylamine hydrochloride
• Pargylamine hydrochloride

Pargyline Hydrochloride

CAS: 306-07-0

Color and Shape: Neat

Ref: 61-FOR1912.00

Pargyline, HCl

CAS: 306-07-0

Formula: C₁₁H₁₄ClN

Purity: 99%

Color and Shape: Solid

Molecular weight: 195.6886

Ref: IN-DA0030N6

Pargyline hydrochloride

CAS: 306-07-0

Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.

Formula: C₁₁H₁₄ClN

Purity: 99.41% - 99.91%

Color and Shape: Solid

Molecular weight: 195.69

Ref: TM-T1578

Pargyline hydrochloride

CAS: 306-07-0

Pargyline hydrochloride

Purity: ≥98%

Molecular weight: 195.69g/mol

Ref: 54-BUP17536

Pargyline hydrochloride

CAS: 306-07-0

Pargyline hydrochloride

Purity: 98%

Color and Shape: Solid

Molecular weight: 195.69g/mol

Ref: 54-OR54425

Pargyline hydrochloride

CAS: 306-07-0

Formula: C₁₁H₁₃N·HCl

Purity: ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 195.69

Ref: 7W-GP7491

Pargyline Hydrochloride

Controlled Product

CAS: 306-07-0

Formula: C₁₁H₁₃N·ClH

Color and Shape: Neat

Molecular weight: 195.69

Ref: 86-MM1912.00

Pargyline Hydrochloride

Controlled Product

CAS: 306-07-0

Applications Pargyline Hydrochloride acts as a monoamine oxidase (MAO) inhibitor, decreasing systolic blood pressure steadily in subjects. Antihypertensive.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fuentes, J. et al.: Eur. J. Pharm., 57, 21 (1979); Knoll, J. et al.: Tabei, R. et al.: Clin. Pharm. Ther., 11, 269 (1970);

Formula: C₁₁H₁₃N·ClH

Color and Shape: Neat

Molecular weight: 195.69

Ref: TR-P193285

N-Benzyl-N-methylprop-2-yn-1-amine hydrochloride

CAS: 306-07-0

Formula: C₁₁H₁₄ClN

Purity: 97%

Color and Shape: Solid

Molecular weight: 195.69

Ref: 10-F336074

N-Methyl-N-propargylbenzylamine HCl

Controlled Product

CAS: 306-07-0

N-Methyl-N-propargylbenzylamine HCl is a nonsteroidal anti-inflammatory drug that inhibits the enzyme cyclooxygenase (COX) and blocks the production of prostaglandins. This drug has low potency, although its selectivity for COX-2 makes it an attractive candidate for treatment of inflammation associated with arthritis. N-Methyl-N-propargylbenzylamine HCl also has been shown to have receptor activity on toll-like receptor 4 in human biological samples. It has been shown to decrease dopamine levels in rats, suggesting that it may be a potential treatment for Parkinson's disease. In addition, this drug was found to decrease epithelial mesenchymal transition and increase expression of p53 protein in prostate cancer cells, as well as inhibit 5HT2 receptors in rat brain tissue. This drug also increases 5HT concentrations and decreases diastolic blood pressure in humans.

Purity: Min. 95%

Ref: 3D-FM41823