CAS 306-14-9

L-Histidyl-L-histidine

Description:

L-Histidyl-L-histidine, with the CAS number 306-14-9, is a dipeptide composed of two histidine amino acids linked by a peptide bond. This compound is characterized by its role in biological systems, particularly in protein synthesis and metabolism. Histidine is an essential amino acid that plays a crucial role in enzyme function and is involved in the synthesis of histamine, a vital neurotransmitter. L-Histidyl-L-histidine exhibits properties typical of peptides, such as solubility in water and the ability to form various conformations depending on the pH and ionic strength of the solution. It may also participate in metal ion coordination due to the presence of imidazole side chains in histidine, which can bind to transition metals. This dipeptide can be studied for its potential applications in biochemistry and pharmacology, particularly in understanding peptide interactions and functions in biological systems. Overall, L-Histidyl-L-histidine serves as an important model for studying peptide behavior and interactions in various biochemical contexts.

Formula: C₁₂H₁₆N₆O₃

InChI: InChI=1/C12H16N6O3/c13-9(1-7-3-14-5-16-7)11(19)18-10(12(20)21)2-8-4-15-6-17-8/h3-6,9-10H,1-2,13H2,(H,14,16)(H,15,17)(H,18,19)(H,20,21)

InChI key: InChIKey=SGCGMORCWLEJNZ-UWVGGRQHSA-N

SMILES: C([C@H](NC([C@H](CC1=CN=CN1)N)=O)C(O)=O)C2=CN=CN2

Synonyms:

• 125: PN: WO2020191245 SEQID: 253 claimed protein
• 128: PN: WO2021061872 SEQID: 128 claimed protein
• 12: PN: US20130123467 SEQID: 12 claimed protein
• <span class="text-smallcaps">L</smallcap>-Histidine, <smallcap>L</span>-histidyl-
• <span class="text-smallcaps">L</smallcap>-Histidine, N-<smallcap>L</span>-histidyl-
• <span class="text-smallcaps">L</smallcap>-Histidyl-<smallcap>L</span>-histidine
• Histidine, N-<span class="text-smallcaps">L</smallcap>-histidyl-, <smallcap>L</span>-
• Histidine, N-<span class="text-smallcaps">L</span>-histidyl-
• Histidylhistidine
• Histidine, N-L-histidyl-
• L-Histidyl-L-histidine
• Histidine, N-L-histidyl-, L-
• L-Histidine, L-histidyl-
• L-Histidine, N-L-histidyl-
• His-His-OH
• 2-[[2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
• N'alpha-histidylhistidine
• (S)-2-[(S)-2-Amino-3-(1H-imidazol-4-yl)propionylamino]-3-(1H-imidazol-4-yl]propionic acid
• H-His-His-OH
• 2-[[2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-imidazol-5-yl)propionic acid
• His-His
• 2-[[2-azanyl-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid

H-His-His-OH

CAS: 306-14-9

Bachem ID: 4028691.

Formula: C₁₂H₁₆N₆O₃

Purity: ≥ 98%

Color and Shape: Whitish Powder

Molecular weight: 292.3

Ref: 01-4028691

H-His-His-OH trifluoroacetate salt

CAS: 306-14-9

H-His-His-OH trifluoroacetate salt is a compound that has been extensively studied for its potential use in antimicrobial peptides. It is a small molecule that inhibits the activity of enzymes by binding to a specific region on the enzyme's surface, thereby preventing the progression of an essential chemical reaction. H-His-His-OH trifluoroacetate salt has been shown to inhibit protein synthesis in bacteria and yeast cells, as well as in model systems. The inhibition of protein synthesis may be due to hydrogen bonding between the hydroxyl group on His and the amino groups on His. H-His-His-OH trifluoroacetate salt also has an inhibitory effect on enzymes catalysis and can enhance their activity when used with another substrate.

Formula: C₁₂H₁₆N₆O₃

Purity: Min. 95%

Molecular weight: 292.29 g/mol

Ref: 3D-FH108319