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CAS 3064731-00-3

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  • PARP14 inhibitor 2
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    PARP14 inhibitor 2

    CAS:
    <p>PARP14 inhibitor2 (Compound 3) is an orally active and highly selective PARP14 inhibitor with an IC50 value of less than 30 nM. It effectively inhibits the mono ADP-ribosyltransferase activity of PARP14 and modulates IFN-γ and IL-4 signaling, thereby reversing pro-tumor macrophage polarization and suppressing anti-tumor inflammatory responses. PARP14 inhibitor2 holds potential for research in PARP14-related conditions such as tumors, atopic dermatitis, and autoimmune diseases.</p>
    Formula:C25H32FN3O4S
    Color and Shape:Solid
    Molecular weight:489.60

    Ref: TM-T207726