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CAS 3067908-20-4

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  • Enpp-1-IN-25
    Targetmol
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    Enpp-1-IN-25

    CAS:
    <p>Enpp-1-IN-25 (Compound 30) is an ENPP1 inhibitor with an IC50 of 8.05 nM and exhibits low oral bioavailability. By inhibiting cGAMP degradation, it effectively activates the intracellular STING pathway. Enpp-1-IN-25 can enhance immune cell infiltration and type I interferon response in the tumor microenvironment, thereby increasing the antitumor efficacy of anti-PD-L1 antibodies. It is applicable for research in cancer immunotherapy.</p>
    Formula:C15H21N5O4S
    Color and Shape:Solid
    Molecular weight:367.423

    Ref: TM-T205138