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CAS 3069831-25-7

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  • HDAC-IN-27 dihydrochloride
    Targetmol
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    HDAC-IN-27 dihydrochloride

    CAS:
    <p>HDAC-IN-27 dihydrochloride (Compound 11h) is a potent, orally active, HDACI class-selective inhibitor, with IC50 values ranging from 0.43 to 3.01 nM for HDAC1-3. This compound exhibits both in vivo and in vitro anticancer activity. HDAC-IN-27 shows significant antiproliferative effects against acute myeloid leukemia (AML) cell lines by inducing apoptosis and histone acetylation (AcHH3 and AcHH4). It is useful for research on acute myeloid leukemia (AML).</p>
    Formula:C20H24Cl2N4O2
    Color and Shape:Solid
    Molecular weight:423.336

    Ref: TM-T206628