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CAS 30747-23-0

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Guanosine, N-acetyl-,2',3',5'-triacetate

Description:
Guanosine, N-acetyl-, 2',3',5'-triacetate, with the CAS number 30747-23-0, is a modified nucleoside derivative of guanosine. This compound features an acetyl group attached to the nitrogen atom of the guanine base, as well as three acetyl groups esterified to the hydroxyl groups on the ribose sugar. The presence of these acetyl groups enhances the lipophilicity of the molecule, which can influence its biological activity and solubility in organic solvents. Guanosine derivatives are often studied for their roles in cellular signaling and as potential therapeutic agents. The triacetate form may exhibit altered pharmacokinetics compared to unmodified guanosine, potentially affecting its interaction with nucleic acid structures and enzymes. Additionally, this compound may be utilized in biochemical research, particularly in studies involving RNA synthesis and modification. As with many nucleoside derivatives, its stability, reactivity, and biological properties can vary significantly based on the specific functional groups present and their positions on the molecule.
Formula:C18H21N5O9
Synonyms:
  • Acetamide,N-(1,6-dihydro-6-oxo-9-b-D-ribofuranosyl-9H-purin-2-yl)-, triacetate (ester) (8CI)
  • N2,2',3',5'-Tetraacetylguanosine
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