CAS 307510-92-5: CFTR(inh)-172

Description: CFTR(inh)-172, with the CAS number 307510-92-5, is a small molecule inhibitor specifically targeting the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This compound is primarily utilized in research settings to study the function of CFTR, which is a chloride channel critical for maintaining the balance of salt and water on epithelial surfaces. CFTR(inh)-172 is known to inhibit the channel's activity, thereby providing insights into the physiological and pathophysiological roles of CFTR in various tissues, particularly in the lungs and pancreas. The compound is often employed in experiments to explore the effects of CFTR inhibition on ion transport and fluid secretion, which are crucial in understanding cystic fibrosis and other related disorders. Additionally, CFTR(inh)-172 has been used to investigate potential therapeutic strategies aimed at modulating CFTR function. Its chemical structure and properties facilitate its role as a selective inhibitor, making it a valuable tool in both basic and applied biomedical research.

Formula: C₁₈H₁₀F₃NO₃S₂

InChI: InChI=1S/C18H10F3NO3S2/c19-18(20,21)12-2-1-3-13(9-12)22-15(23)14(27-17(22)26)8-10-4-6-11(7-5-10)16(24)25/h1-9H,(H,24,25)

InChI key: InChIKey=JIMHYXZZCWVCMI-UHFFFAOYSA-N

SMILES: O=C(O)C1=CC=C(C=C1)C=C2SC(=S)N(C2=O)C3=CC=CC(=C3)C(F)(F)F

Synonyms:

• 3-[(3-Trifluoromethyl)phenyl]-5-[(4-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone
• CFTR(inh)-172
• Benzoic acid, 4-[[4-oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]-
• Cystic fibrosis transmembrane conductance regulator inhibitor CFTR(inh)-172
• 4-[[4-Oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]benzoic acid

Benzoic acid, 4-[[4-oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]-

CAS: 307510-92-5

• Formula: C₁₈H₁₀F₃NO₃S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 409.4021095999999

Cftr(Inh)-172

CAS: 307510-92-5

• Purity: 98%+
• Molecular weight: 409.40g/mol

CFTR(inh)-172

CAS: 307510-92-5

• Purity: 99.93%
• Molecular weight: 409.4g/mol

CFTR(inh)-172

CAS: 307510-92-5

• Formula: C₁₈H₁₀F₃NO₃S₂
• Purity: ≥ 95.0%
• Color and Shape: Yellow powder or solid
• Molecular weight: 409.40

CFTR(inh)-172

CAS: 307510-92-5

CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.

• Formula: C₁₈H₁₀F₃NO₃S₂
• Purity: 98% - 99.72%
• Color and Shape: Solid
• Molecular weight: 409.4

CFTR Inhibitor-172

CAS: 307510-92-5

• Formula: C₁₈H₁₀F₃NO₃S₂
• Color and Shape: Neat
• Molecular weight: 409.402

3-[(3-Trifluoromethyl)Phenyl]-5-[(4-Carboxyphenyl)Methylene]-2-Thioxo-4-Thiazolidinone

CAS: 307510-92-5

3-[(3-Trifluoromethyl)Phenyl]-5-[(4-Carboxyphenyl)Methylene]-2-Thioxo-4-Thiazolidinone is a model system that can be used to study the role of Toll-like …

• Formula: C₁₈H₁₀F₃NO₃S₂
• Purity: Min. 95%
• Molecular weight: 409.4 g/mol