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CAS 3077-61-0

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4-hydroxy-N-methylbenzenesulfonamide

Description:
4-Hydroxy-N-methylbenzenesulfonamide, also known as sulfanilamide, is an organic compound characterized by its sulfonamide functional group, which is a key feature in many pharmaceuticals. This compound has a molecular structure that includes a benzene ring substituted with a hydroxyl group and a methylsulfonamide group. It is typically a white to off-white crystalline solid that is soluble in water and polar organic solvents. The presence of the hydroxyl group contributes to its ability to form hydrogen bonds, enhancing its solubility and reactivity. This compound exhibits antibacterial properties, making it relevant in medicinal chemistry, particularly in the development of sulfa drugs. Additionally, it may participate in various chemical reactions, including sulfonation and substitution reactions, due to the reactivity of the sulfonamide group. Its safety profile and potential toxicity should be considered in handling and application, as with many sulfonamide derivatives. Overall, 4-hydroxy-N-methylbenzenesulfonamide is significant in both industrial and pharmaceutical contexts.
Formula:C7H9NO3S
InChI:InChI=1/C7H9NO3S/c1-8-12(10,11)7-4-2-6(9)3-5-7/h2-5,8-9H,1H3
SMILES:CNS(=O)(=O)c1ccc(cc1)O
Synonyms:
  • benzenesulfonamide, 4-hydroxy-N-methyl-
  • 4-Hydroxy-N-methylbenzenesulfonamide
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