CAS 308103-40-4

2-Acetylphenylboronic acid

Description:

2-Acetylphenylboronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a phenyl ring that also contains an acetyl substituent. This compound typically appears as a white to off-white solid and is soluble in polar organic solvents. Its structure features a boron atom bonded to a phenyl group and a hydroxyl group, which imparts acidic properties. The acetyl group enhances its reactivity, making it useful in various chemical reactions, particularly in Suzuki coupling reactions, which are essential for forming carbon-carbon bonds in organic synthesis. Additionally, 2-acetylphenylboronic acid can act as a ligand in coordination chemistry and has potential applications in medicinal chemistry due to its ability to interact with biological targets. Its reactivity and functional versatility make it a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals. Proper handling and storage are essential, as with many boronic acids, to maintain stability and prevent degradation.

Formula: C₈H₉BO₃

InChI: InChI=1S/C8H9BO3/c1-6(10)7-4-2-3-5-8(7)9(11)12/h2-5,11-12H,1H3

InChI key: InChIKey=ZKAOVABYLXQUTI-UHFFFAOYSA-N

SMILES: B(O)(O)C1=C(C(C)=O)C=CC=C1

Synonyms:

• B-(2-Acetylphenyl)boronic acid
• Boronic acid, (2-acetylphenyl)-
• 2-Acetylphenylboronic acid
• 2-Acetylbenzeneboronic acid
• Boronic acid, B-(2-acetylphenyl)-

2-Acetylbenzeneboronic acid, 97%

CAS: 308103-40-4

2-Acetylphenylboronic acid is a reactant used for a variety of coupling reactions, as well as synthesis and hydroxy masking, Suzuki-Miyaura cross-coupling reactions, rhodium-catalyzed annulation of ynamides, transient masking of hydroxy groups, cationic palladium complex-catalyzed diastereoselective

Formula: C₈H₉BO₃

Purity: 97%

Color and Shape: White to yellow, Powder and/or chunks

Molecular weight: 163.97

Ref: 02-H27327

Boronic acid, B-(2-acetylphenyl)-

CAS: 308103-40-4

Formula: C₈H₉BO₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 163.9663

Ref: IN-DA0031D9

2-Acetylbenzeneboronic acid

CAS: 308103-40-4

2-Acetylbenzeneboronic acid

Formula: C₈H₉BO₃

Purity: 95%

Color and Shape: faint beige solid

Molecular weight: 163.96626g/mol

Ref: 54-OR10312

2-Acetylphenylboronic acid

CAS: 308103-40-4

Formula: C₈H₉BO₃

Molecular weight: 163.97

Ref: 7W-GK8174

2-Acetylphenylboronic acid

CAS: 308103-40-4

Formula: C₈H₉BO₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 163.97

Ref: 10-F036621

2-Acetylphenylboronic Acid

Controlled Product

CAS: 308103-40-4

Applications 2-Acetylphenylboronic Acid is a reactant used in the synthesis of potent, selective phenylimidazole-based tissue factor/factor VIIa (FVIIa) inhibitors.
References Glunz, P.W., et. al.: Bioorg. Med. Chem. Lett., 25, 21699 (2015)

Formula: C₈H₉BO₃

Color and Shape: Neat

Molecular weight: 163.97

Ref: TR-A186930