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CAS 3081246-18-3

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  • CDK9/EZH2-IN-1

    CAS:
    <p>CDK9/EZH2-IN-1 is a dual-target inhibitor of CDK9 and EZH2 with IC50 values of 83.9 nM and 108.6 nM, respectively. It induces apoptosis and causes DNA double-strand breaks (DSB). Additionally, CDK9/EZH2-IN-1 inhibits the proliferation of MKN45, MDA-MB-453, and SW620 cancer cells, with respective IC50 values of 136.3 nM, 171.3 nM, and 315.7 nM.</p>
    Formula:C47H59N11O4S2
    Color and Shape:Solid
    Molecular weight:906.17