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CAS 3081383-46-9

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  • (S)-dHTC1
    Targetmol
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    (S)-dHTC1

    CAS:
    <p>(S)-dHTC1 is a molecular glue degrader specifically targeting the transcriptional coactivator ENL. It exhibits high affinity binding to E3 ligase only upon formation of the ENL:(S)-dHTC1 complex, with an IC50 of 93 nM. In MV4;11 cells, (S)-dHTC1 degrades ENL with a DC50 of 26 nM. This compound can be utilized for acute myeloid leukemia research.</p>
    Formula:C33H40N8O6S
    Color and Shape:Solid
    Molecular weight:676.786

    Ref: TM-T206969