CAS 30827-99-7

4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride

Description:

4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, with the CAS number 30827-99-7, is a chemical compound characterized by its sulfonamide structure, which includes a sulfonyl fluoride group attached to a benzene ring. This compound typically appears as a white to off-white solid and is soluble in polar solvents such as water and alcohols. It is often utilized in biochemical research and pharmaceutical applications due to its ability to act as a sulfonylating agent, which can modify proteins and other biomolecules. The presence of the aminoethyl group enhances its reactivity and potential for biological interactions. As a hydrochloride salt, it is more stable and easier to handle compared to its free base form. Safety precautions should be taken when handling this compound, as sulfonyl fluorides can be reactive and potentially hazardous. Proper storage conditions and protective equipment are recommended to mitigate any risks associated with exposure.

Formula: C₈H₁₀FNO₂S·ClH

InChI: InChI=1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H

InChI key: InChIKey=WRDABNWSWOHGMS-UHFFFAOYSA-N

SMILES: S(F)(=O)(=O)C1=CC=C(CCN)C=C1.Cl

Synonyms:

• (2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
• 2,4,6-Tribromo-3,5-Difluoropyridine
• 2-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride
• 2-[4-(Fluorosulfonyl)phenyl]ethanaminium chloride
• 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride (1:1)
• 4-(2-Aminoethyl)benzenesulfonylfluoride hydrochloride
• Aebsf
• Benzenesulfonyl fluoride, 4-(2-aminoethyl)-, hydrochloride
• Benzenesulfonyl fluoride, 4-(2-aminoethyl)-, hydrochloride (1:1)
• Benzenesulfonyl fluoride, p-(2-aminoethyl)-, hydrochloride
• Pefabloc
• Pefabloc SC
• Pefabloc SC Plus

4-(2-Aminoethyl)benzenesulfonyl Fluoride Hydrochloride [for Biochemical Research]

CAS: 30827-99-7

Formula: C₈H₁₀FNO₂S·HCl

Purity: >99.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 239.69

Ref: 3B-A2215

4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97%

CAS: 30827-99-7

AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiti

Formula: C₈H₁₁ClFNO₂S

Purity: 97%

Color and Shape: Powder, White

Molecular weight: 239.69

Ref: 02-H26473

4-(2-Aminoethyl)benzenesulfonyl fluoride, HCl

CAS: 30827-99-7

Formula: C₈H₁₁ClFNO₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 239.6948

Ref: IN-DA0031FD

4-(2-Aminoethyl)benzenesulphonyl fluoride hydrochloride

CAS: 30827-99-7

4-(2-Aminoethyl)benzenesulphonyl fluoride hydrochloride

Formula: C₈H₁₀FNO₂S·ClH

Purity: >98%

Color and Shape: white to off white powder

Molecular weight: 239.69g/mol

Ref: 54-BIMB2003

AEBSF hydrochloride

CAS: 30827-99-7

AEBSF hydrochloride

Purity: ≥98%

Molecular weight: 239.69g/mol

Ref: 54-BUP17006

AEBSF, Hydrochloride

CAS: 30827-99-7

M01245 - AEBSF, Hydrochloride

Formula: C₈H₁₁ClFNO₂S

Purity: 98%

Color and Shape: Crystalline Powder,Powder

Molecular weight: 239.69

Ref: 10-M01245

AEBSF hydrochloride

CAS: 30827-99-7

AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin.

Formula: C₈H₁₁ClFNO₂S

Purity: 98% - 99.81%

Color and Shape: White Powder

Molecular weight: 239.69

Ref: TM-T6370

4-(2-Aminoethyl)benzenesulphonyl fluoride hydrochloride

CAS: 30827-99-7

4-(2-Aminoethyl)benzenesulphonyl fluoride hydrochloride

Formula: C₈H₁₀FNO₂S·ClH

Purity: 98%

Color and Shape: white to off-white powder

Molecular weight: 239.69484g/mol

Ref: 54-PC5642

AEBSF hydrochloride

CAS: 30827-99-7

Formula: C₈H₁₀FNO₂S·HCl

Purity: ≥ 98.0%

Color and Shape: White to off-white powder or solid

Molecular weight: 239.69

Ref: 7W-GE4678

AEBSF Hydrochloride

Controlled Product

CAS: 30827-99-7

Applications AEBSF Hydrochloride is an irreversible serine protease inhibitor.
References Diatchuk, V., et. al.: J. Biol. Chem., 272, 13292 (1997)

Formula: C₈H₁₁ClFNO₂S

Color and Shape: Neat

Molecular weight: 239.69

Ref: TR-A325300

4-(2-Aminoethyl)-benzenesulfonylfluoride hydrochloride

CAS: 30827-99-7

4-(2-Aminoethyl)-benzenesulfonylfluoride hydrochloride, also known as AEBSF, is an irreversible serine protease inhibitor. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. It inhibits by acylation of the active site of the enzyme. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture, in concentrations of up to 0.25 mM. Aqueous solutions are stable between pH 5-6; limited stability above pH 7.5.

Formula: C₈H₁₁ClFNO₂S

Purity: Min. 98.0 Area-%

Molecular weight: 239.70 g/mol

Ref: 3D-A-5440

AEBSF Hydrochloride extrapure AR, 98%

CAS: 30827-99-7

Formula: C₈H₁₀FNO₂S·HCl

Purity: min. 98%

Color and Shape: White, Crystalline powder

Molecular weight: 239.69

Ref: SR-89204