CAS 30918-54-8

Polyinosinic acid

Description:

Polyinosinic acid, often abbreviated as poly(I), is a synthetic polynucleotide that consists of repeating units of inosinic acid, which is the ribonucleotide form of inosine. It is characterized by its high molecular weight and is typically found in a linear form. Poly(I) is known for its role as a potent immunostimulant, often used in research to mimic viral RNA and activate immune responses. It can induce the production of interferons and other cytokines, making it valuable in studies related to antiviral therapies and vaccine development. The substance is soluble in water and exhibits a negative charge due to its phosphate backbone, which influences its interactions with proteins and other biomolecules. Polyinosinic acid is also utilized in various biochemical assays and as a component in drug delivery systems. Its CAS number, 30918-54-8, is a unique identifier that facilitates its recognition in scientific literature and databases. Overall, poly(I) serves as an important tool in molecular biology and immunology research.

Formula: (C₁₀H₁₃N₄O₈P)n

InChI: InChI=1/C10H13N4O8P/c15-5-3(1-21-23(18,19)20)22-7(6(5)16)9-13-4-8(14-9)11-2-12-10(4)17/h2-3,5-7,15-16H,1H2,(H2,18,19,20)(H2,11,12,13,14,17)/t3-,5-,6-,7-/m1/s1

InChI key: InChIKey=GRSZFWQUAKGDAV-KQYNXXCUSA-N

SMILES: O[C@H]1[C@H](N2C3=C(N=C2)C(=O)N=CN3)O[C@H](COP(=O)(O)O)[C@H]1O

Synonyms:

• (1S)-1,4-Anhydro-1-(6-oxo-6,9-dihydro-3H-purin-8-yl)-5-O-phosphono-D-ribitol
• 5′-Inosinic acid, homopolymer
• 5′-Inosinic acid, polymers
• D-ribitol, 1,4-anhydro-1-C-(6,9-dihydro-6-oxo-3H-purin-8-yl)-, 5-(dihydrogen phosphate), (1S)-
• NSC 120952
• Poly I
• Poly(5′-inosinic acid)
• Poly(IMP)
• Poly(rI)
• [(2R,3S,4R,5S)-3,4-dihydroxy-5-(6-oxo-3,9-dihydropurin-8-yl)tetrahydrofuran-2-yl]methyl dihydrogen phosphate
• Polyinosinic acid sodium salt
• Polyinosinic acid
• Polyinosinic acid sodium salt，Poly I, POLY I-Na
• POLYINOSINIC ACID POTASSIUM SALT
• Polyinosinic Acid (90%)
• POLY RL POTASSIUM SALT
• [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)-2-oxolanyl]methyl dihydrogen phosphate
• 5’-Inosinicacid,homopolymer
• Poly(5’-inosinicacid)
• Polyinosinic acid USP/EP/BP
• POLYINOSINIC ACID (5') POTASSIUM SALT
• POLYINOSINIC ACID POT. SALT, LYOPH., MR ~1200000
• Polyinosinic acid (Poly I)
• polyinosinicacidpot.salt
• POLYINOSINIC ACID TRIPOTASSIUM SALT
• Polyinosinic acid sodium

Polyinosinicacid

CAS: 30918-54-8

Formula: C₁₀H₁₃N₄O₈P

Purity: 90%

Color and Shape: Solid

Molecular weight: 348.2060

Ref: IN-DA0031MY

Polyinosinic acid

CAS: 30918-54-8

Polyinosinic acid: single-strand, TLR3 agonist, boosts immune response, has immune regulation uses.

Formula: (C₁₀H₁₃N₄O₈P)x

Color and Shape: Solid

Ref: TM-T74760

Polyinosinic Acid (90%)

Controlled Product

CAS: 30918-54-8

Applications Polyinosinic Acid is an oligolysines used in nucleic acid binding and other biomedical applications.
References Roviello,G. N., et al.: Int. J. Nanomedicine, 11, 5897 (2016)

Formula: C₁₀H₁₃N₄O₈P

Purity: 90%

Color and Shape: Neat

Molecular weight: 348.21

Ref: TR-P698975