CAS 3092-17-9: Midodrine hydrochloride

Description: Midodrine hydrochloride is a synthetic medication primarily used as a vasopressor to treat orthostatic hypotension, a condition characterized by abnormally low blood pressure upon standing. It acts as an alpha-1 adrenergic agonist, leading to vasoconstriction and increased blood pressure. The chemical formula for midodrine hydrochloride is C12H17ClN2O4S, and it features a sulfonamide group, which contributes to its pharmacological activity. The substance is typically administered in its hydrochloride salt form, enhancing its solubility and stability. Midodrine is known for its relatively short half-life, necessitating multiple doses throughout the day to maintain therapeutic effects. Common side effects may include piloerection, urinary retention, and hypertension, particularly when lying down. Due to its mechanism of action, midodrine is contraindicated in patients with severe heart disease or those with a history of urinary retention. Overall, midodrine hydrochloride is a valuable therapeutic agent for managing specific forms of low blood pressure, although careful monitoring is essential to avoid adverse effects.

Formula: C₁₂H₁₈N₂O₄·ClH

InChI: InChI=1S/C12H18N2O4.ClH/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13;/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16);1H

InChI key: InChIKey=MGCQZNBCJBRZDT-UHFFFAOYSA-N

SMILES: Cl.O=C(NCC(O)C1=CC(OC)=CC=C1OC)CN

Synonyms:

• (±)-Midodrin hydrochloride
• -[+/-]-1-[2,5-Dimethoxyphenyl]-2-Glycinamidoethanol Hydrochloride
• 2-Amino-N-(2-(2,5-Dimethoxyphenyl)-2-Hydroxyethyl)-Acetamidmonohydrochlo
• 2-Amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)acetamide hydrochloride
• A 4020 Linz
• Acetamide, 2-amino-N-(β-hydroxy-2,5-dimethoxyphenethyl)-, hydrochloride
• Acetamide, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-, hydrochloride (1:1)
• Acetamide, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-, monohydrochloride
• Acetamide,2-Amino-N-(Beta-Hydroxy-2,5-Dimethoxyphenethyl)-,Monohydrochloride,
• Alphamine
• Amatine
• Gutron
• Hipertan
• Metligene
• Metligine
• Midamine
• N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]glycinamide hydrochloride (1:1)
• ProAmatine
• St 1085
• St. Peter 224
• Ts 701
• Midodrine hydrochloride

Midodrine Hydrochloride

CAS: 3092-17-9

Aromatic cyclic amides (including cyclic carbamates) an

• Formula: C₁₂H₁₈N₂O₄·HCl
• Color and Shape: Powder
• Molecular weight: 254.12666

Midodrine hydrochloride

CAS: 3092-17-9

Midodrine, metabolized to desglymidodrine, activates alpha-1 receptors, raising blood pressure without CNS effects. It's a …

• Formula: C₁₂H₁₉ClN₂O₄
• Purity: 99.36% - 99.79%
• Color and Shape: Crystalline Solid
• Molecular weight: 290.74

Midodrine hydrochloride

CAS: 3092-17-9

• Purity: 99.36%
• Molecular weight: 290.74g/mol