CAS 30925-18-9

N-(tert-Butoxycarbonyl)aspartic acid benzyl ester

Description:

N-(tert-Butoxycarbonyl)aspartic acid benzyl ester, with the CAS number 30925-18-9, is a chemical compound commonly used in organic synthesis, particularly in the field of peptide chemistry. This compound features a tert-butoxycarbonyl (Boc) protecting group, which is often employed to protect amine functionalities during chemical reactions. The presence of the benzyl ester moiety enhances the compound's lipophilicity, making it more soluble in organic solvents, which is advantageous for various synthetic applications. The aspartic acid backbone contributes to its potential as a building block in peptide synthesis, allowing for the introduction of specific amino acid sequences. The compound is typically characterized by its stability under acidic and neutral conditions, while it can be deprotected under basic conditions or through specific catalytic methods. Its utility in synthesizing peptides and other complex molecules makes it a valuable intermediate in pharmaceutical and biochemical research. As with all chemical substances, proper handling and safety protocols should be observed due to potential hazards associated with its use.

Formula: C₁₆H₂₁NO₆

InChI: InChI=1S/C16H21NO6/c1-16(2,3)23-15(21)17-12(9-13(18)19)14(20)22-10-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,17,21)(H,18,19)/t12-/m0/s1

InChI key: InChIKey=LDRWTKQWSXGSTM-LBPRGKRZSA-N

SMILES: [C@H](C(OCC1=CC=CC=C1)=O)(NC(OC(C)(C)C)=O)CC(O)=O

Synonyms:

• (2R)-4-(benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid (non-preferred name)
• (3S)-3-[(2-Methylpropan-2-yl)oxycarbonylamino]-4-oxo-4-phenylmethoxybutanoic acid
• (3S)-4-(benzyloxy)-3-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid (non-preferred name)
• (S)-2-(tert-Butoxycarbonylamino)succinic acid benzyl ester
• (S)-4-(Benzyloxy)-3-[(tertbutoxycarbonyl)amino]-4-oxobutanoic acid
• 4-(Benzyloxy)-3-[(Tert-Butoxycarbonyl)Amino]-4-Oxobutanoic Acid (Non-Preferred Name)
• <span class="text-smallcaps">L</span>-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(phenylmethyl) ester
• Boc-L-aspartic acid 1-benzyl ester
• Boc-L-aspartic acid a-benzyl ester
• N-(tert-Butoxycarbonyl)-L-aspartic acid α-benzyl ester
• N-(tert-Butoxycarbonyl)aspartic acid 1-benzyl ester
• N-(tert-Butoxycarbonyl)aspartic acid benzyl ester
• N-a-BOC-L-Asp-OBzl
• N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid α-benzyl ester
• α-Benzyl N-(tert-butoxycarbonyl)-<span class="text-smallcaps">L</span>-aspartate
• Boc-Asp-OBzl
• α-Benzyl N-(tert-butoxycarbonyl)-L-aspartate

1-Benzyl N-(tert-Butoxycarbonyl)-L-aspartate

CAS: 30925-18-9

Formula: C₁₆H₂₁NO₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 323.35

Ref: 3B-B2408

L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(phenylmethyl) ester

CAS: 30925-18-9

Formula: C₁₆H₂₁NO₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 323.3410

Ref: IN-DA0031OV

Boc-Asp-OBzl

CAS: 30925-18-9

Formula: C₁₆H₂₁NO₆

Molecular weight: 323.35

Ref: 7W-GM1616

Boc-L-Aspartic acid 1-benzyl ester

CAS: 30925-18-9

Boc-L-Aspartic acid 1-benzyl ester

Formula: C₁₆H₂₁NO₆

Purity: 98%

Color and Shape: white solid

Molecular weight: 323.34g/mol

Ref: 54-OR480637

Boc-Asp-OBzl

CAS: 30925-18-9

M03269 - Boc-Asp-OBzl

Formula: C₁₆H₂₁NO₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 323.345

Ref: 10-M03269

Boc-Asp-OBzl

CAS: 30925-18-9

Boc-Asp-OBzl is a hydrolysate that contains aspartic acid and has been shown to inhibit the activity of the enzyme peptidylglycine alpha-amidating monooxygenase. It is an orthogonal inhibitor that can be used to study the role of aspartic acid in peptide synthesis. Boc-Asp-OBzl has also been shown to inhibit rat liver microsomes, with an IC50 value of about 0.4 mM, and it did not affect the activity of vitamin K1 or other enzymes. This inhibitor can also be used in experiments on rat liver microsomes and solubilized rat liver preparations.br>

Formula: C₁₆H₂₁NO₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 323.34 g/mol

Ref: 3D-FB34277