CAS 31036-80-3: Lofexidine

Description: Lofexidine is a selective alpha-2 adrenergic agonist primarily used in the management of opioid withdrawal symptoms. It acts by reducing the release of norepinephrine, thereby alleviating symptoms associated with opioid cessation. The chemical formula of Lofexidine is C11H12Cl2N2, and it features a bicyclic structure that contributes to its pharmacological properties. This compound is typically administered in the form of hydrochloride salt, enhancing its solubility and bioavailability. Lofexidine is known for its relatively favorable side effect profile compared to other medications used for opioid withdrawal, making it a valuable option in clinical settings. It is important to note that while Lofexidine can help manage withdrawal symptoms, it is not a substitute for comprehensive addiction treatment. As with any medication, its use should be guided by a healthcare professional, considering potential interactions and contraindications. Overall, Lofexidine represents a significant advancement in the therapeutic approach to opioid dependence.

Formula: C₁₁H₁₂Cl₂N₂O

InChI: InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)

InChI key: InChIKey=KSMAGQUYOIHWFS-UHFFFAOYSA-N

SMILES: ClC1=CC=CC(Cl)=C1OC(C2=NCCN2)C

Synonyms:

• 1H-Imidazole, 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-
• (±)-Lofexidine
• 2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole
• 2-(1-(2,6-Dichlorophenoxy)Ethyl)-4,5-Dihydro-1H-Imidazole
• 2-Imidazoline, 2-[1-(2,6-dichlorophenoxy)ethyl]-
• 2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole
• 1H-imidazole, 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-
• 2-{1-[(2,6-dichlorophenyl)oxy]ethyl}-4,5-dihydro-1H-imidazole
• (±)-2-[1-(2,6-Dichlorophenoxy)ethyl]-2-imidazoline
• 2-(a-(2,6-Dichlorophenoxy)ethyl)2-imidazoline
• Lofexidine

1H-Imidazole, 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-

CAS: 31036-80-3

• Formula: C₁₁H₁₂Cl₂N₂O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 259.1318

Lofexidine

CAS: 31036-80-3

• Purity: ≥98%
• Molecular weight: 259.13g/mol

Lofexidine

CAS: 31036-80-3

• Formula: C₁₁H₁₂Cl₂N₂O
• Purity: (HPLC) ≥ 98.0%
• Color and Shape: White to beige powder
• Molecular weight: 259.13

Lofexidine

CAS: 31036-80-3

• Formula: C₁₁H₁₂Cl₂N₂O
• Molecular weight: 259.13

Lofexidine

CAS: 31036-80-3

Lofexidine is a selective α2-receptor agonist, Lofexidine reduces narcotic withdrawal symptoms.

• Formula: C₁₁H₁₂Cl₂N₂O
• Purity: 98.78%
• Color and Shape: Solid
• Molecular weight: 259.13

LOFEXIDINE

CAS: 31036-80-3

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 259.1300048828125

Lofexidine

CAS: 31036-80-3

Lofexidine is a centrally acting α2 adrenergic agonist that has been used for the treatment …

• Formula: C₁₁H₁₂Cl₂N₂O
• Purity: Min. 95%
• Molecular weight: 259.13 g/mol