CAS 3109-01-1

Betamethasone-17-ketone

Description:

Betamethasone-17-ketone, with the CAS number 3109-01-1, is a synthetic corticosteroid that exhibits anti-inflammatory and immunosuppressive properties. It is a derivative of betamethasone, characterized by the presence of a ketone group at the 17 position of the steroid structure. This modification enhances its potency and efficacy in treating various conditions, including allergies, skin disorders, and autoimmune diseases. Betamethasone-17-ketone is typically administered in topical formulations or as an injectable, depending on the condition being treated. The compound is known for its ability to inhibit the release of inflammatory mediators and modulate immune responses, making it valuable in clinical settings. Additionally, it has a relatively low mineralocorticoid activity, which reduces the risk of fluid retention and electrolyte imbalances commonly associated with other corticosteroids. As with all corticosteroids, careful consideration of dosage and duration of treatment is essential to minimize potential side effects, such as adrenal suppression and increased susceptibility to infections.

Formula: C₂₀H₂₅FO₃

InChI: InChI=1S/C20H25FO3/c1-11-8-15-14-5-4-12-9-13(22)6-7-19(12,3)20(14,21)16(23)10-18(15,2)17(11)24/h6-7,9,11,14-16,23H,4-5,8,10H2,1-3H3/t11-,14-,15-,16-,18-,19-,20-/m0/s1

InChI key: InChIKey=IZLVPOBNINIXJM-BUMFJRDRSA-N

SMILES: F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)C(=O)[C@@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]

Synonyms:

• (11β,16β)-9-Fluoro-11-hydroxy-16-methylandrosta-1,4-diene-3,17-dione
• 9-Fluoro-11beta-hydroxy-16beta-methylandrosta-1,4-diene-3,17-dione
• 9α-Fluoro-11β-hydroxy-16β-methyl-1,4-androstadiene-3,17-dione
• Androsta-1,4-diene-3,17-dione, 9-fluoro-11-hydroxy-16-methyl-, (11beta,16beta)-
• Androsta-1,4-diene-3,17-dione, 9-fluoro-11-hydroxy-16-methyl-, (11β,16β)-
• Androsta-1,4-diene-3,17-dione, 9-fluoro-11β-hydroxy-16β-methyl-
• Betamethasone-17-ketone
• NSC 52437

17-Oxo Betamethasone

CAS: 3109-01-1

Formula: C₂₀H₂₅FO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 332.4091

Ref: IN-DA00C2UZ

Betamethasone Impurity 10

CAS: 3109-01-1

Formula: C₂₀H₂₅FO₃

Color and Shape: White To Off-White Solid

Molecular weight: 332.42

Ref: 4Z-B-065053

Betamethasone-17-ketone (9α-Fluoro-11β-hydroxy-16β-methylandrosta-1,4-diene-3,17-dione)

Controlled Product

CAS: 3109-01-1

Formula: C₂₀H₂₅FO₃

Color and Shape: Neat

Molecular weight: 332.41

Ref: 86-MM0200.13

17-Oxo betamethasone

Controlled Product

CAS: 3109-01-1

17-Oxo betamethasone is a metabolite of prednisolone and is formed by the activation of prednisolone by 17-hydroxylase. It has been postulated that this metabolite may be involved in the regulation of hormone synthesis. This compound is not known to have any biological function, but it can be found in wastewater. Activated 17-oxo betamethasone has been shown to have an aerobic biodegradability of 0.6% per day and an environmental half-life of 3 days. The main reaction route for activated 17-oxo betamethasone is through hydrolysis, which results in the formation of inactive metabolites such as methylprednisolone and 5β-dihydroxy-17α,20α-[(1S)-1,2,3]trihydroxytestosterone.

Formula: C₂₀H₂₅FO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 332.41 g/mol

Ref: 3D-FO26639

Betamethasone-​17-​ketone

CAS: 3109-01-1

Formula: C₂₀H₂₅FO₃

Molecular weight: 332.42

Ref: ST-EA-CP-B25047