CAS 31135-55-4

Triiodothyronine sulfate

Description:

Triiodothyronine sulfate, also known by its CAS number 31135-55-4, is a sulfated derivative of the thyroid hormone triiodothyronine (T3). This compound is characterized by the presence of three iodine atoms attached to the phenolic rings, which is typical of thyroid hormones, and a sulfate group that enhances its solubility in water. Triiodothyronine sulfate plays a role in the regulation of various physiological processes, including metabolism, growth, and development. It is often involved in the transport and metabolism of T3 within the body, influencing its bioavailability and activity. The compound is typically found in biological fluids and tissues, where it may serve as a reservoir for the active hormone. Its synthesis and degradation are tightly regulated, reflecting the complex interplay of thyroid hormones in endocrine function. As a sulfated compound, it may exhibit different pharmacokinetic properties compared to its non-sulfated counterparts, impacting its therapeutic applications and biological effects.

Formula: C₁₅H₁₂I₃NO₇S

InChI: InChI=1S/C15H12I3NO7S/c16-9-6-8(1-2-13(9)26-27(22,23)24)25-14-10(17)3-7(4-11(14)18)5-12(19)15(20)21/h1-4,6,12H,5,19H2,(H,20,21)(H,22,23,24)/t12-/m0/s1

InChI key: InChIKey=XBQYQXVJBNDCGY-LBPRGKRZSA-N

SMILES: O(C1=C(I)C=C(C[C@@H](C(O)=O)N)C=C1I)C2=CC(I)=C(OS(=O)(=O)O)C=C2

Synonyms:

• Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, hydrogen sulfate, L-
• Thyronine, triiodo-, hydrogen sulfate
• 3,5-Diiodo-O-[3-iodo-4-(sulfooxy)phenyl]-L-tyrosine
• L-Tyrosine, 3,5-diiodo-O-[3-iodo-4-(sulfooxy)phenyl]-
• Triiodothyronine sulfate

3,3’,5-Triiodo-L-thyronine 4’-O-Sulfate-13C6 sodium salt

Controlled Product

CAS: 31135-55-4

Formula: C₆C₉H₁₁I₃NNaO₇S

Color and Shape: Neat

Molecular weight: 758.975

Ref: TR-T795446

3,3’,5-Triiodo-L-thyronine 4’-O-Sulfate

CAS: 31135-55-4

Applications 3,3’,5-Triiodo-L-thyronine 4’-O-Sulfate is the sulfoconjugated metabolite of 3,3’,5-Triiodo-L-thyronine (T795380).
References Rooda, S.J. et al.: J. Clin. Endocrinol. Metab., 69, 552 (1989); Everts, M. E. et al.: Metab. Clin. Exp., 43, 1282 (1994); Pinna, G. et al.: Endocrinology, 143, 1789 (2002);

Formula: C₁₅H₁₂I₃NO₇S

Color and Shape: Neat

Molecular weight: 731.04

Ref: TR-T795395

Triiodothyronine Sulfate

CAS: 31135-55-4

Triiodothyronine sulfate: Hypothyroidism prodrug, metabolizes into active thyroid hormone T3, binds and activates TRβ1.

Formula: C₁₅H₁₁I₃NNaO₇S

Purity: 98%

Color and Shape: Solid

Molecular weight: 753.02

Ref: TM-T29011