CAS 31136-61-5

Grayanotoxane-5,6,7,10,16-pentol, 2,3-epoxy-, 7-acetate, (2β,3β,6β,7α)-

Description:

Grayanotoxane-5,6,7,10,16-pentol, 2,3-epoxy-, 7-acetate, (2β,3β,6β,7α)-, commonly referred to by its CAS number 31136-61-5, is a chemical compound belonging to the class of grayanotoxins, which are naturally occurring toxins found in certain species of plants, particularly those in the Ericaceae family, such as rhododendrons and azaleas. This compound is characterized by its complex polycyclic structure, which includes multiple hydroxyl groups and an epoxy group, contributing to its biological activity. Grayanotoxane is known for its ability to interfere with sodium ion channels in nerve and muscle cells, leading to potential toxic effects when ingested. Symptoms of grayanotoxin poisoning can include nausea, vomiting, and cardiovascular disturbances. The compound's structural features, including the presence of an acetate group, influence its solubility and reactivity. Due to its toxicological properties, it is important to handle this substance with care in both laboratory and environmental contexts.

Formula: C₂₂H₃₄O₇

InChI: InChI=1S/C22H34O7/c1-10(23)28-17-15(24)22(27)14(13-16(29-13)18(22,2)3)20(5,26)12-7-6-11-8-21(12,17)9-19(11,4)25/h11-17,24-27H,6-9H2,1-5H3/t11-,12+,13+,14+,15-,16+,17-,19-,20-,21-,22+/m1/s1

InChI key: InChIKey=IONWCZKSTMAXMV-CRRNJOFASA-N

SMILES: O(C(C)=O)[C@H]1[C@]23[C@]([C@@](C)(O)[C@]4([C@](O)([C@@H]1O)C(C)(C)[C@@]5([C@]4(O5)[H])[H])[H])(CC[C@](C2)([C@](C)(O)C3)[H])[H]

Synonyms:

• 5,7a-Methano-7aH-cyclohept[6,7]azuleno[1,2-b]oxirene, grayanotoxane-5,6,7,10,16-pentol deriv.
• 7,9a-Methano-9aH-cyclopenta[b]heptalene-4,8,10,11,11a(1H)-pentol, 2,3-epoxydodecahydro-1,1,4,8-tetramethyl-, 11-acetate, (2R,3S,3aS,4R,4aR,7R,8R,9aR,10S,11R,11aR)-
• Lyoniatoxin
• Grayanotoxane-5,6,7,10,16-pentol, 2,3-epoxy-, 7-acetate, (2β,3β,6β,7α)-
• Lyoniol A

Lyoniol-A

CAS: 31136-61-5

Lyoniol-A is a toxic component from poisonous tree in Japan(Lyonia ovalifolia var. elliptica).

Formula: C₂₂H₃₄O₇

Color and Shape: Solid

Molecular weight: 410.5

Ref: TM-T33037