CAS 312-73-2

2-(Trifluoromethyl)benzimidazole

Description:

2-(Trifluoromethyl)benzimidazole is an organic compound characterized by the presence of a benzimidazole core substituted with a trifluoromethyl group at the second position. This compound typically exhibits a white to off-white crystalline appearance and is known for its relatively high stability due to the presence of the aromatic ring and the electron-withdrawing trifluoromethyl group, which can influence its reactivity and solubility. The trifluoromethyl group enhances the lipophilicity of the molecule, making it potentially useful in various applications, including pharmaceuticals and agrochemicals. Additionally, the compound may exhibit interesting biological activities, which can be attributed to the structural features of the benzimidazole moiety. Its properties, such as melting point, boiling point, and solubility, can vary based on the specific conditions and purity of the sample. As with many fluorinated compounds, it is important to handle 2-(trifluoromethyl)benzimidazole with care due to potential environmental and health impacts associated with fluorinated substances.

Formula: C₈H₅F₃N₂

InChI: InChI=1/C8H7ClO4S/c1-13-8(10)6-2-4-7(5-3-6)14(9,11)12/h2-5H,1H3

InChI key: InChIKey=MXFMPTXDHSDMTI-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C=1NC=2C(N1)=CC=CC2

Synonyms:

• 1H-Benzimidazole, 2-(trifluoromethyl)-
• 2-(Trifluoromethyl)-1H-1,3-benzodiazole
• 2-(Trifluoromethyl)-1H-benzo[d]imidazole
• 2-(trifluoromethyl)-1H-benzimidazole
• 2-Trifluoromethyl-1H-benzoimidazole
• Benzimidazole, 2-(trifluoromethyl)-
• Methyl 4-(Chlorosulfonyl)Benzoate
• NSC 512765
• NSC 97013
• 2-(Trifluoromethyl)benzimidazole
• 2-(trifluoromethyl)-1h-benzimidazol
• 3-TRIFLUOROMETHYL BENZIMIDAZOLE
• 1H-Benzimidazole,2-(trifluoromethyl)-(9CI)
• RARECHEM AQ NN 0072

1H-Benzimidazole, 2-(trifluoromethyl)-

CAS: 312-73-2

Formula: C₈H₅F₃N₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 186.1339

Ref: IN-DA00I5UK

2-(Trifluoromethyl)benzimidazole

CAS: 312-73-2

2-(Trifluoromethyl)benzimidazole

Purity: ≥98%

Molecular weight: 186.1339g/mol

Ref: 54-BUP15969

2-(Trifluoromethyl)-1H-benzimidazole

CAS: 312-73-2

2-(Trifluoromethyl)-1H-benzimidazole

Purity: 98%

Color and Shape: Grey Powder

Molecular weight: 186.13g/mol

Ref: 54-PC7727

2-(Trifluoromethyl)benzimidazole

CAS: 312-73-2

2-(Trifluoromethyl)benzimidazole a novel in vitro and in vivo inducer of iron death with antiparasitic activity.

Formula: C₈H₅F₃N₂

Purity: 99.37% - ≥98%

Color and Shape: Solid

Molecular weight: 186.1339

Ref: TM-Fr12535

2-(Trifluoromethyl)benzimidazole

CAS: 312-73-2

2-(Trifluoromethyl)benzimidazole (TFB) is a synthetic trifluoromethyl-substituted benzimidazole. It has been shown to have potent tuberculostatic activity and is effective against a wide range of protozoan parasites, including Leishmania, Trichomonas vaginalis, and Giardia lamblia. TFB binds to the target molecule by forming hydrogen bonds with the amino acid side chains on the enzyme's surface. TFB inhibits energy metabolism in cancer cells and causes them to undergo apoptosis through activation of caspase-3. The diploid rat liver cell line HepG2 was used for in vivo studies that showed that TFB inhibits ethylene diamine deaminase activity, which is required for the synthesis of purines and pyrimidines from ethylene diamine.

Formula: C₈H₅F₃N₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 186.13 g/mol

Ref: 3D-FT37003

2-(Trifluoromethyl)-benzimidazole

CAS: 312-73-2

Formula: C₈H₅F₃N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 186.137

Ref: 10-F005953