CAS 312-84-5

D-Serine

Description:

D-Serine is an amino acid that serves as a co-agonist at the N-methyl-D-aspartate (NMDA) receptor, playing a crucial role in neurotransmission and synaptic plasticity in the central nervous system. It is a chiral molecule, existing as the D-enantiomer of serine, and is classified as a non-proteinogenic amino acid. D-Serine is soluble in water and exhibits a neutral pH in solution. Its structure features a hydroxymethyl group, which contributes to its biological activity. D-Serine is involved in various physiological processes, including cognitive functions and neurodevelopment, and has been studied for its potential therapeutic effects in conditions such as schizophrenia and neurodegenerative diseases. Additionally, it is synthesized in the body from L-serine through the action of the enzyme serine racemase. Due to its role in the nervous system, D-serine is of significant interest in neuroscience research, particularly in understanding synaptic mechanisms and the modulation of glutamatergic signaling.

Formula: C₃H₇NO₃

InChI: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1

InChI key: InChIKey=MTCFGRXMJLQNBG-UWTATZPHSA-N

SMILES: [C@H](C(O)=O)(CO)N

Synonyms:

• (2R)-2-Amino-3-hydroxypropanoic acid
• (R)-2-Amino-3-hydroxypropanoic acid
• (R)-Serine
• <span class="text-smallcaps">D</span>-Serine
• D-2-Amino-3-hydroxypropanoic acid
• D-Ser
• D-Ser-OH
• D-Serin
• D-serina
• H-D-Ser-OH
• Nsc 77689
• Serine, <span class="text-smallcaps">D</span>-
• Serine, D-
• D-Serine

D-Serine

CAS: 312-84-5

Formula: C₃H₇NO₃

Purity: >98.5%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 105.09

Ref: 3B-S0033

D-Serine, 99%

CAS: 312-84-5

D-Serine is involved in the biosynthesis of purines, pyrimidines, and other amino acids. D-Serine also is an agonist of glycine site of the NMDA-type glutamate receptor. It also acts as Lacosamide intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar prod

Formula: C₃H₇NO₃

Purity: 99%

Color and Shape: Crystals or powder or crystalline powder, White to pale cream

Molecular weight: 105.09

Ref: 02-A11353

D-Serine

CAS: 312-84-5

Formula: C₃H₇NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 105.0926

Ref: IN-DA00I5UL

D-Serine

CAS: 312-84-5

D-Serine

Formula: C₃H₇NO₃

Purity: 95%

Color and Shape: white crystalline solid

Molecular weight: 105.09g/mol

Ref: 54-BIS2001

D-Serine ((R)-Glycine EP Impurity G)

CAS: 312-84-5

Formula: C₃H₇NO₃

Molecular weight: 105.09

Ref: 4Z-S-126023

D-Serine

CAS: 312-84-5

D-Serine

Purity: ≥98%

Molecular weight: 105.09g/mol

Ref: 54-BUP18256

D-Serine

CAS: 312-84-5

Formula: C₃H₇NO₃

Purity: 98.5 - 101.5 % (dried basis)

Color and Shape: White to off-white powder

Molecular weight: 105.09

Ref: 7W-GM2756

D-Serine

CAS: 312-84-5

D-Serine ((R)-Serine) is an endogenous amino acid,is a potent co-agonist at the NMDA glutamate receptor.

Formula: C₃H₇NO₃

Purity: 99.57% - 99.93%

Color and Shape: Solid

Molecular weight: 105.09

Ref: TM-T8394

D-Serine

Controlled Product

CAS: 312-84-5

Applications A proteinogenic amino acids involved in the biosynthesis of purines and pyrimidines. Inhibitor of serine palmitoyltransferase. A neuromodulator.
References Junjaud, G. et al.: J. Neurochem., 98, 1159 (2006); Hanada, K. et al.: FEBS Lett., 474, 63 (2000); Pollegionni, L. et al.: Cell. Mol. Life Sci., 67, 2387 (2010);

Formula: C₃H₇NO₃

Color and Shape: Neat

Molecular weight: 105.09

Ref: TR-S270975

D-Serine

CAS: 312-84-5

D-Serine is an amino acid that has been shown to have a physiological function in the brain. It is an endogenous coagonist at the glycine site on the N-methyl-D-aspartate (NMDA) receptor. D-Serine has been shown to be neuroprotective and reduce neuronal death in experimental models of Parkinson's disease, Alzheimer's disease, and stroke. D-Serine also has a role in energy metabolism, as it can be converted to serine by racemase. This conversion is critical for neuronal survival during periods of prolonged fasting or low glucose levels. The production of d-serine from l-serine via racemase may serve as a potential biomarker for certain diseases such as Parkinson's disease and Alzheimer's disease.

Formula: C₃H₇NO₃

Color and Shape: White Powder

Molecular weight: 105.09 g/mol

Ref: 3D-FS27815

D-Serine

CAS: 312-84-5

Formula: C₃H₇NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 105.093

Ref: 10-F011887

D-Serine extrapure, 99%

CAS: 312-84-5

Formula: C₃H₇NO₃

Purity: min. 99%

Color and Shape: White to off-white, Crystalline compound, Clear, Colourless

Molecular weight: 105.1

Ref: SR-53457

Cycloserine Impurity 1 (D-serine)

CAS: 312-84-5

Formula: C₃H₇NO₃

Molecular weight: 105.09

Ref: ST-EA-CP-C86008

Cycloserine Impurity 1 (D-serine)

CAS: 312-84-5

Formula: C₃H₇NO₃

Molecular weight: 105.09

Ref: 4Z-C-11304