CAS 312-93-6
:Dexamethasone phosphate
Description:
Dexamethasone phosphate is a synthetic corticosteroid and a derivative of dexamethasone, primarily used for its anti-inflammatory and immunosuppressive properties. It is characterized by its phosphate ester form, which enhances its solubility in water compared to its parent compound. This solubility makes it suitable for parenteral administration. The substance is often utilized in the treatment of various conditions, including allergies, autoimmune disorders, and certain types of cancer. Dexamethasone phosphate acts by binding to glucocorticoid receptors, leading to the modulation of gene expression and subsequent reduction of inflammation and immune response. Its pharmacokinetics include rapid absorption and a relatively long half-life, allowing for effective therapeutic dosing. Common side effects may include increased susceptibility to infections, fluid retention, and alterations in glucose metabolism. As with other corticosteroids, careful monitoring is essential to mitigate potential adverse effects, especially with long-term use. Overall, dexamethasone phosphate is a valuable medication in clinical practice, particularly in managing inflammatory and autoimmune conditions.
Formula:C22H30FO8P
InChI:InChI=1S/C22H30FO8P/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30)/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
InChI key:InChIKey=VQODGRNSFPNSQE-CXSFZGCWSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@](F)([C@]4(C)C(CC3)=CC(=O)C=C4)[C@@H](O)C1)[H])(C[C@@H](C)[C@@]2(C(COP(=O)(O)O)=O)O)[H]
Synonyms:- (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione
- Betnelan phosphate
- Dexamethasone 21-dihydrogen phosphate
- Dexamethasone 21-phosphate
- Dexamethasone orthophosphate
- Dexamethasone phosphate
- Micromethason
- Pregna-1,4-Diene-3,20-Dione, 9-Fluoro-11,17-Dihydroxy-16-Methyl-21-(Phosphonooxy)-, (11Beta,16Alpha)-
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, (11β,16α)-
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-(dihydrogen phosphate)
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-phosphate
- Wymesone
- See more synonyms
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Found 11 products.
Dexamethasone Phosphate
CAS:Halogenated derivatives of adrenal cortical hormonesFormula:C22H30FO8PColor and Shape:White PowderMolecular weight:472.16623Dexamethasone phosphate
CAS:<p>Dexamethasone phosphate is a synthetic adrenal corticosteroid. It also has potent anti-inflammatory properties.</p>Formula:C22H30FO8PColor and Shape:SolidMolecular weight:472.44Dexamethasone Phosphate-D5 (Major)
CAS:Controlled ProductFormula:C222H5H25FO8PColor and Shape:NeatMolecular weight:477.47Dexamethasone 21-Phosphate Dimer Sodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Dexamethasone 21-Phosphate Dimer is a derivative of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Formula:C44H56F2NaO12PColor and Shape:White SolidMolecular weight:868.87Dexamethasone Phosphate
CAS:<p>Applications A pro-drug of Dexamethasone (D298800), an anti-inflammatory glucocorticoid. It was found that liposomal DXM-P inhibited both chronic inflammation and joint destruction, whereas free DXM-P failed to prevent joint destruction.<br>References Kodelja, V., et al.: J. Immunol., 160, 1411 (1998), Metselaar, J., et al.: Arthritis Rheum., 48, 2059 (2003), Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (2004), Martinez, F., et al.: Front Biosci., 13, 453 (2008),<br></p>Formula:C22H30FO8PColor and Shape:White To Light BrownMolecular weight:472.44Dexamethasone 21-Phosphate Dimer-d6 Sodium Salt
CAS:Controlled ProductFormula:C44D6H50F2O12P·NaColor and Shape:NeatMolecular weight:874.90Dexamethasone 21-Phosphate Dimer-d10 Sodium Salt
CAS:Controlled ProductFormula:C44D10H46F2NaO12PColor and Shape:NeatMolecular weight:878.93Dexamethasone 21-Phosphate Dimer-d8 Sodium Salt
CAS:Controlled ProductFormula:C44D8H48F2NaO12PColor and Shape:NeatMolecular weight:876.918Dexamethasone phosphate
CAS:Dexamethasone phosphateFormula:C22H30FO8PPurity:99.2%Color and Shape:White To Light BrownMolecular weight:472.16623
