CAS 312295-62-8

4-Chloro-6-(trifluoromethoxy)quinazoline

Description:

4-Chloro-6-(trifluoromethoxy)quinazoline is a synthetic organic compound characterized by its quinazoline core, which is a bicyclic structure containing two nitrogen atoms. The presence of a chlorine atom at the 4-position and a trifluoromethoxy group at the 6-position significantly influences its chemical properties and reactivity. This compound is typically a solid at room temperature and is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting various biological pathways. The trifluoromethoxy group enhances lipophilicity and may improve the compound's bioavailability. Additionally, the chlorine substituent can affect the compound's electronic properties, potentially influencing its interaction with biological targets. As with many halogenated compounds, it may exhibit unique reactivity patterns, making it of interest in various chemical syntheses and applications. Safety data should be consulted for handling, as halogenated compounds can pose environmental and health risks.

Formula: C₉H₄ClF₃N₂O

InChI: InChI=1S/C9H4ClF3N2O/c10-8-6-3-5(16-9(11,12)13)1-2-7(6)14-4-15-8/h1-4H

InChI key: InChIKey=ZGIDAXLBBURWOL-UHFFFAOYSA-N

SMILES: ClC=1C2=C(C=CC(OC(F)(F)F)=C2)N=CN1

Synonyms:

• Quinazoline, 4-chloro-6-(trifluoromethoxy)-
• 4-Chloro-6-(trifluoromethoxy)quinazoline

4-Chloro-6-(trifluoromethoxy)quinazoline

CAS: 312295-62-8

Versatile small molecule scaffold

Formula: C₉H₄ClF₃N₂O

Purity: Min. 95%

Molecular weight: 248.59 g/mol

Ref: 3D-MMA29562