CAS 312306-89-1

Neuromedin U-25 (Human)

Description:

Neuromedin U-25 (Human) is a neuropeptide that plays a significant role in various physiological processes, including the regulation of appetite, circadian rhythms, and stress responses. It is a member of the neuromedin U family, which is known for its involvement in the modulation of smooth muscle contraction and neurotransmission. The peptide is characterized by its ability to bind to specific receptors, influencing cellular signaling pathways. Neuromedin U-25 is typically synthesized in the central nervous system and peripheral tissues, contributing to its diverse biological effects. Its structure consists of a sequence of amino acids that confer its biological activity, and it is often studied for its potential implications in metabolic disorders and neurobiology. The CAS number 312306-89-1 uniquely identifies this specific peptide, facilitating its recognition in scientific literature and databases. Research continues to explore its therapeutic potential, particularly in conditions related to obesity and stress-related disorders.

Neuromedin U-25 (human)

CAS: 312306-89-1

Neuromedin U is a neuropeptide which is widely distributed in the gut and central nervous system. Initially isolated from porcine spinal cord it was named for its uterine contractile activity. In fasted rats neuromedin U expression in certain brain areas is lower than in fed rats. In animal studies with neuromedin-23 (rat) overnight food intake is significantly reduced indicating that neuromedin U may be a physiological regulator of food intake. IC₅₀ values for the binding of neuromedin U-25 (human) to the human neuromedin U receptors NMU1R and NMU2R are 2.7 nM and 1.8 nM, respectively.

Formula: C₁₄₁H₂₀₃N₄₁O₃₈

Purity: 95.3%

Color and Shape: White Lyophilisate

Molecular weight: 3080.42

Ref: 01-4037521

Neuromedin U-25 (human)

CAS: 312306-89-1

Ref: 7W-GW9580

Neuromedin U-25 (human) trifluoroacetate salt

CAS: 312306-89-1

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Formula: C₁₄₁H₂₀₃N₄₁O₃₈

Purity: Min. 95%

Molecular weight: 3,080.37 g/mol

Ref: 3D-FN109534