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CAS 31251-03-3

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Fluotrimazole

Description:
Fluotrimazole, with the CAS number 31251-03-3, is an antifungal agent belonging to the imidazole class of compounds. It is primarily used in the treatment of various fungal infections, particularly those caused by dermatophytes and yeasts. The substance exhibits broad-spectrum antifungal activity by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting their integrity and function. Fluotrimazole is typically administered topically, making it effective for localized infections. Its chemical structure features a fluorinated imidazole ring, which enhances its potency and selectivity against fungal pathogens. The compound is generally well-tolerated, with a low incidence of side effects, although some individuals may experience localized irritation or allergic reactions. As with many antifungal agents, resistance can develop, necessitating careful consideration of its use in clinical settings. Overall, fluotrimazole represents a valuable option in the antifungal therapeutic arsenal, particularly for superficial fungal infections.
Formula:C22H16F3N3
InChI:InChI=1S/C22H16F3N3/c23-22(24,25)20-13-7-12-19(14-20)21(28-16-26-15-27-28,17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-16H
InChI key:InChIKey=LXMQMMSGERCRSU-UHFFFAOYSA-N
SMILES:C(C1=CC(C(F)(F)F)=CC=C1)(C2=CC=CC=C2)(C3=CC=CC=C3)N4C=NC=N4
Synonyms:
  • 1-{Diphenyl[3-(trifluormethyl)phenyl]methyl}-1H-1,2,4-triazol
  • 1-{Diphenyl[3-(trifluoromethyl)phenyl]methyl}-1H-1,2,4-triazole
  • 1H-1,2,4-Triazole, 1-[α,α-diphenyl-m-(trifluoromethyl)benzyl]-
  • 1H-1,2,4-triazole, 1-[diphenyl[3-(trifluoromethyl)phenyl]methyl]-
  • 250-534-5
  • B 6660
  • Diphenyl(3-trifluoromethylphenyl)(1,2,4-triazol-1-yl)methane
  • Fluotrimazol
  • Fluotrimazole
  • NSC 303302
  • Persulon 6660
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