CAS 312636-16-1

4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol

Description:

4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol, identified by its CAS number 312636-16-1, is a chemical compound characterized by its complex structure, which includes a thiazole ring and multiple aromatic systems. This compound typically exhibits properties such as being a solid at room temperature, with potential applications in pharmaceuticals or as a research chemical due to its unique functional groups. The presence of the chlorophenyl and thiazole moieties suggests that it may possess biological activity, possibly acting as an inhibitor or modulator in various biochemical pathways. Its solubility can vary depending on the solvent, and it may exhibit specific reactivity patterns due to the amino and hydroxyl groups present in its structure. Additionally, the compound's stability, melting point, and other physical properties would be influenced by its molecular interactions and the presence of substituents. Safety data should be consulted for handling and usage, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₁₅H₁₁ClN₂OS

InChI: InChI=1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13(19)8-6-12/h1-9,19H,(H,17,18)

InChI key: InChIKey=ZFGXZJKLOFCECI-UHFFFAOYSA-N

SMILES: N(C1=NC(=CS1)C2=CC=C(Cl)C=C2)C3=CC=C(O)C=C3

Synonyms:

• Phenol, 4-[[4-(4-chlorophenyl)-2-thiazolyl]amino]-
• SKI 2
• SA 792728
• 4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol

4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol

CAS: 312636-16-1

Formula: C₁₅H₁₁ClN₂OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 302.7786

Ref: IN-DA0037DR

SKI II

CAS: 312636-16-1

SKI II

Purity: ≥98%

Molecular weight: 302.78g/mol

Ref: 54-BUP11083

SKI II

CAS: 312636-16-1

Formula: C₁₅H₁₁ClN₂OS

Molecular weight: 302.78

Ref: 7W-GL2879

SKI II

CAS: 312636-16-1

SKI II is a selective non-ATP S1P receptor inhibitor with an IC50 of 0.5 μM; it doesn't inhibit PKCα, PI3K, or ERK2.

Formula: C₁₅H₁₁ClN₂OS

Purity: 99.34% - 99.93%

Color and Shape: Solid

Molecular weight: 302.78

Ref: TM-T6673

4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol

CAS: 312636-16-1

4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol is a chemical that has been used in analytical and in vitro methods to study the cellular physiology of cells. It was found to inhibit sphingosine kinase, which is an enzyme that is involved in the synthesis of sphingosine. The inhibition of this enzyme leads to decreased levels of sphingosine and the effect on the cell. 4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol can also affect mitochondrial membrane potential and cyclase activity, which may be useful for treating hyperproliferative diseases such as breast cancer.

Formula: C₁₅H₁₁ClN₂OS

Purity: Min. 95%

Molecular weight: 302.78 g/mol

Ref: 3D-FC137468

SKI-II

CAS: 312636-16-1

Purity: 98%

Molecular weight: 302.028

Ref: 10-F862444

SKI II

Controlled Product

CAS: 312636-16-1

Applications SKI II is a nonlipid inhibitor of sphingosine kinase. SKI II s orally bioavailable and has shown significant inhibition of tumor growth in mice.
References French, K.J., et. al.: Cancer Res., 63, 5962 (2003); French, K.J., et. al.: J. Pharmacol. Exp. Ther., 318, 596 (2006)

Formula: C₁₅H₁₁ClN₂OS

Color and Shape: Neat

Molecular weight: 302.78

Ref: TR-S553000