CAS 312693-42-8

(4-chloro-3-fluoro-phenyl)-iodo-zinc

Description:

(4-chloro-3-fluoro-phenyl)-iodo-zinc, with the CAS number 312693-42-8, is an organozinc compound characterized by the presence of a zinc atom bonded to an iodo-substituted aromatic ring. This compound typically features a phenyl group that is substituted with both chlorine and fluorine atoms, which can influence its reactivity and properties. The presence of the iodine atom suggests potential applications in cross-coupling reactions, such as the Suzuki or Negishi reactions, where organozinc reagents are commonly employed. The chlorine and fluorine substituents can enhance the compound's lipophilicity and electronic properties, making it useful in various synthetic applications in organic chemistry. Additionally, the compound may exhibit unique physical properties, such as solubility in organic solvents, and could be of interest in medicinal chemistry for the development of pharmaceuticals. As with many organometallic compounds, handling should be done with care due to potential reactivity and toxicity.

Formula: C₆H₃ClFIZn

InChI: InChI=1/C6H3ClF.HI.Zn/c7-5-3-1-2-4-6(5)8;;/h1,3-4H;1H;/q;;+1/p-1/rC6H3ClFIZn/c7-5-2-1-4(10-9)3-6(5)8/h1-3H

InChI key: HGHUUGDDALXKID-UHFFFAOYSA-M

SMILES: C1=C=CC(C(=C1)Cl)F.I.[Zn]

Synonyms:

• (4-chloro-3-fluoro-phenyl)-iodo-zinc
• 4-chloro-3-fluorophenylzinc iodide solution
• 4-CHLORO-3-FLUOROPHENYLZINC IODIDE
• 4-CHLORO-3-FLUOROPHENYLZINC IODIDE, 0.5M SOLUTION IN TETRAHYDROFURAN