CAS 312693-72-4

2'-Deoxyguanosine hydrate

Description:

2'-Deoxyguanosine hydrate is a nucleoside that plays a crucial role in the structure of DNA. It consists of a guanine base attached to a deoxyribose sugar, which lacks an oxygen atom at the 2' position, distinguishing it from ribonucleosides. The hydrate form indicates the presence of water molecules associated with the compound, which can influence its solubility and stability. This substance is typically white to off-white in appearance and is soluble in water, making it suitable for various biochemical applications. In biological systems, 2'-deoxyguanosine is involved in the synthesis of DNA and is a building block for nucleic acids. It can also participate in various biochemical pathways, including those related to cellular metabolism and signaling. The compound is of interest in research related to genetics, molecular biology, and pharmacology, particularly in studies involving nucleic acid interactions and the development of therapeutic agents. Its CAS number, 312693-72-4, uniquely identifies this specific chemical entity in chemical databases.

Formula: C₁₀H₁₅N₅O₅

InChI: InChI=1/C10H13N5O4.H2O/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6;/h3-6,16-17H,1-2H2,(H3,11,13,14,18);1H2/t4-,5+,6+;/m0./s1

Synonyms:

• 2'-Deoxyguanosine Monohydrate(2'-dG.H₂ O)

2'-Deoxyguanosine Monohydrate, Synthetic, >98% (Dry Basis)

CAS: 312693-72-4

Thermo Scientific 2'-Deoxyguanosine Monohydrate Synthetic

Formula: C₁₀H₁₅N₅O₅

Purity: 98%

Color and Shape: White crystalline powder

Molecular weight: 285.26

Ref: 02-J14304

2'-Deoxyguanosine monohydrate

CAS: 312693-72-4

Formula: C₁₀H₁₅N₅O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 285.2566

Ref: IN-DA00BC3Y

2'-Deoxyguanosine monohydrate

CAS: 312693-72-4

2'-Deoxyguanosine monohydrate

Purity: ≥98%

Molecular weight: 285.26g/mol

Ref: 54-BUP15878

2'-Deoxyguanosine monohydrate

CAS: 312693-72-4

2'-Deoxyguanosine monohydrate

Formula: C₁₀H₁₃N₅O₄·H₂O

Purity: 98%

Color and Shape: white powder

Molecular weight: 285.26g/mol

Ref: 54-OR960833

2'-Deoxyguanosine monohydrate

CAS: 312693-72-4

Formula: C₁₀H₁₃N₅O₄·H₂O

Purity: ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 285.26

Ref: 7W-GL7240

2'-Deoxyguanosine monohydrate

CAS: 312693-72-4

Formula: C₁₀H₁₃N₅O₄

Purity: 95%~99%

Molecular weight: 267.245

Ref: BP-BP4232

2'-Deoxyguanosine monohydrate

CAS: 312693-72-4

2'-Deoxyguanosine monohydrate, lacking an oxygen, is DNA's nucleoside. It can turn into 8-OHdG, a marker for DNA damage linked to cancer.

Formula: C₁₀H₁₅N₅O₅

Purity: 99.73%

Color and Shape: Solid

Molecular weight: 285.26

Ref: TM-T4715

2’-Deoxyguanosine Monohydrate

Controlled Product

CAS: 312693-72-4

Applications 2’-Deoxyguanosine Monohydrate is a nucleoside analog.
References Krenitsky, T.A., et al.: Biochemistry, 20, 3615 (1981), Chapeau, M.-C., et al.: Chem. Res. Toxicol., 4, 636 (1991),

Formula: C₁₀H₁₃N₅O₄·H₂O

Color and Shape: White To Beige

Molecular weight: 285.26

Ref: TR-D239550

2'-Deoxyguanosine-1',2',3',4',5'-13C5 Monohydrate

Controlled Product

CAS: 312693-72-4

Applications Isotope labelled analogue of 2’-Deoxyguanosine (D239550), a nucleoside analog.
References Krenitsky, T.A., et al.: Biochemistry, 20, 3615 (1981), Chapeau, M.-C., et al.: Chem. Res. Toxicol., 4, 636 (1991),

Formula: C₅₁₃C₅H₁₅N₅O₅

Color and Shape: Neat

Molecular weight: 290.22

Ref: TR-D239555

2'-Deoxyguanosine monohydrate

CAS: 312693-72-4

2'-Deoxyguanosine monohydrate is a nucleoside that has been shown to inhibit the synthesis of DNA in human cells. It has also been shown to have a role in the regulation of energy metabolism and mitochondrial functions. 2'-Deoxyguanosine monohydrate binds to the enzyme polymerase chain reaction, which prevents the reverse transcription process from occurring. This nucleoside is involved in the biological studies of cytokine production, such as IL-2 receptor binding and calcium pantothenate-dependent activation of nuclear DNA replication.

Formula: C₁₀H₁₃N₅O₄·H₂O

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 285.26 g/mol

Ref: 3D-ND06306

2′-Deoxyguanosine monohydrate

CAS: 312693-72-4

Formula: C₁₀H₁₅N₅O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 285.26

Ref: 10-F053507

2-Deoxyguanosine Monohydrate extrapure, 99%

CAS: 312693-72-4

Formula: C₁₀H₁₃N₅O₄·H₂O

Purity: min. 99%

Color and Shape: White, Crystalline powder

Molecular weight: 285.24

Ref: SR-22350

1'-Deoxyguanosine Monohydrate-1’-d

Controlled Product

CAS: 312693-72-4

Applications Isotope labelled analogue of 2’-Deoxyguanosine (D239550), a nucleoside analog.
References Krenitsky, T.A., et al.: Biochemistry, 20, 3615 (1981), Chapeau, M.-C., et al.: Chem. Res. Toxicol., 4, 636 (1991),

Formula: C₁₀DH₁₂N₅O₄·H₂O

Color and Shape: Neat

Molecular weight: 286.263

Ref: TR-D239556

2'-Deoxyguanosine-[15N5] monohydrate

CAS: 312693-72-4

2'-Deoxyguanosine-[15N5] monohydrate is a chemical compound that has been shown to have anticancer activity in colorectal adenocarcinoma cells. The high-activity form of this compound is produced by the addition of a 15N isotope, which can be detected using an electrochemical detector. This compound inhibits the enzyme DNA methyltransferase, preventing the addition of methyl groups to DNA and thereby inhibiting cell growth. 2'-Deoxyguanosine-[15N5] monohydrate also has anti-inflammatory properties due to its ability to inhibit IL-2 receptor signaling.

Formula: C₁₀H₁₃N₅O₄·H₂O

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 285.26 g/mol

Ref: 3D-ND170583