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CAS 312707-99-6

:

3-chloro-N-(3-hydroxyphenyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

Description:
3-Chloro-N-(3-hydroxyphenyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is a complex organic compound characterized by its unique structural features, including a pyrazolo[1,5-a]pyrimidine core, which is a bicyclic structure known for its biological activity. The presence of a chloro group and a trifluoromethyl group enhances its lipophilicity and may influence its interaction with biological targets. The hydroxyl group on the phenyl ring can participate in hydrogen bonding, potentially increasing the compound's solubility and reactivity. Additionally, the thienyl substituent contributes to the compound's electronic properties and may affect its pharmacological profile. This compound is of interest in medicinal chemistry, particularly for its potential therapeutic applications, possibly as an anti-inflammatory or anticancer agent. Its specific interactions and efficacy would depend on its ability to bind to target proteins or enzymes, which can be influenced by its overall molecular geometry and electronic characteristics. As with many such compounds, further studies would be necessary to fully elucidate its biological activity and potential applications.
Formula:C18H10ClF3N4O2S
InChI:InChI=1S/C18H10ClF3N4O2S/c19-14-15(17(28)23-9-3-1-4-10(27)7-9)25-26-13(18(20,21)22)8-11(24-16(14)26)12-5-2-6-29-12/h1-8,27H,(H,23,28)
InChI key:UDUBAPJKXAAXPM-UHFFFAOYSA-N
SMILES:C1=CC(=CC(=C1)O)NC(=O)C2=NN3C(=CC(=NC3=C2Cl)C4=CC=CS4)C(F)(F)F
Synonyms:
  • 3-chloro-N-(3-hydroxyphenyl)-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
  • Pyrazolo[1,5-a]pyrimidine-2-carboxamide, 3-chloro-N-(3-hydroxyphenyl)-5-(2-thienyl)-7-(trifluoromethyl)-
  • 3-chloro-N-(3-hydroxyphenyl)-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
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