CAS 3130-72-1

Myristoyl-CoA

Description:

Myristoyl-CoA, with the CAS number 3130-72-1, is a fatty acyl-CoA derivative formed from myristic acid, a saturated fatty acid containing 14 carbon atoms. This compound plays a crucial role in various biochemical processes, particularly in lipid metabolism and cellular signaling. Myristoyl-CoA is characterized by its long hydrophobic carbon chain, which contributes to its role in membrane dynamics and protein modification. It serves as a substrate for acylation reactions, where it can attach to proteins, influencing their localization and function within the cell. Additionally, Myristoyl-CoA is involved in the synthesis of complex lipids and can participate in energy production through β-oxidation. Its presence is essential in various metabolic pathways, including those related to energy storage and utilization. As a CoA derivative, it is also involved in the activation of fatty acids for subsequent metabolic processes. Overall, Myristoyl-CoA is a vital intermediate in cellular metabolism, linking fatty acid metabolism to broader physiological functions.

Formula: C₃₅H₆₂N₇O₁₇P₃S

InChI: InChI=1S/C35H62N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-26(44)63-19-18-37-25(43)16-17-38-33(47)30(46)35(2,3)21-56-62(53,54)59-61(51,52)55-20-24-29(58-60(48,49)50)28(45)34(57-24)42-23-41-27-31(36)39-22-40-32(27)42/h22-24,28-30,34,45-46H,4-21H2,1-3H3,(H,37,43)(H,38,47)(H,51,52)(H,53,54)(H2,36,39,40)(H2,48,49,50)/t24-,28-,29-,30+,34-/m1/s1

InChI key: InChIKey=DUAFKXOFBZQTQE-QSGBVPJFSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OCC([C@H](C(NCCC(NCCSC(CCCCCCCCCCCCC)=O)=O)=O)O)(C)C)(=O)O)(=O)O)[C@H]1OP(=O)(O)O

Synonyms:

• Coenzyme A, S-myristate
• Coenzyme A, S-tetradecanoate
• Coenzyme A, tetradecanoyl-
• Myristoyl-coa
• Myristoyl-coenzyme A
• Myristyl coenzyme A
• Myristyl-CoA
• S-Tetradecanoyl-coenzyme A
• S-{1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} tetradecanethioate (non-preferred name)
• Tetradecanethioic acid, S-ester with coenzyme A
• Tetradecanoyl coenzyme A
• Tetradecanoyl-coa

Tetradecanoyl Coenzyme A free acid

CAS: 3130-72-1

Formula: C35H62N7O17P3S

Purity: >95%

Color and Shape: Solid

Molecular weight: 977.89

Ref: 48-19-1400

Myristoyl Coenzyme A, Free acid

CAS: 3130-72-1

Purity: 95%

Molecular weight: 977.314

Ref: 10-C300048

Myristoyl coenzyme A

CAS: 3130-72-1

Myristoyl coenzyme A is a potential drug that inhibits the binding of human pathogens to protein. It also has been shown to have potential as an inhibitor for reactions involving myristoylation, which is a process where proteins are modified with myristic acid. Myristoyl coenzyme A was synthesized using titration calorimetry and in vitro assays. The compound has been shown to have the ability to inhibit polymerase chain reaction (PCR) and reduce the growth of bacteria in vitro. Myristoyl coenzyme A may be useful in treating metabolic disorders and infectious diseases such as AIDS, tuberculosis, and malaria.

Formula: C₃₅H₆₂N₇O₁₇P₃S·H₂O

Purity: Min. 90%

Color and Shape: White Powder

Molecular weight: 995.91 g/mol

Ref: 3D-NM47200