CAS 3130-96-9

DL-Triiodothyronine

Description:

DL-Triiodothyronine, commonly known as liothyronine, is a synthetic form of the thyroid hormone triiodothyronine (T3). It plays a crucial role in regulating metabolism, growth, and development in the body. The chemical formula for DL-Triiodothyronine is C15H12I3N, and it features three iodine atoms, which are essential for its biological activity. This compound is typically administered in the form of sodium salt and is used therapeutically to treat hypothyroidism and certain types of goiter. Its mechanism of action involves binding to thyroid hormone receptors, influencing gene expression and metabolic processes. DL-Triiodothyronine is characterized by its relatively high potency compared to thyroxine (T4), making it effective in rapidly increasing metabolic rates. It is important to monitor its use carefully, as excessive doses can lead to symptoms of hyperthyroidism, including increased heart rate, anxiety, and weight loss. The substance is classified as a prescription medication and should be used under medical supervision to ensure appropriate dosing and to mitigate potential side effects.

Formula: C₁₅H₁₂I₃NO₄

InChI: InChI=1/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)

InChI key: InChIKey=AUYYCJSJGJYCDS-UHFFFAOYSA-N

SMILES: O(C1=C(I)C=C(CC(C(O)=O)N)C=C1I)C2=CC(I)=C(O)C=C2

Synonyms:

• 2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
• 3,3',5-Triiodo-DL-thyronine
• 3,3′,5-Triiodo-<span class="text-smallcaps">DL</span>-thyronine
• 3,5,3'-Triiodo-DL-thyronine
• 3,5,3′-Triiodo-<span class="text-smallcaps">DL</span>-thyronine
• <span class="text-smallcaps">DL</span>-Triiodothyronine
• <span class="text-smallcaps">DL</span>-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-
• Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, <span class="text-smallcaps">DL</span>-
• Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, DL-
• DL-3,3,5-triiodothyronine
• DL-Triiodothyronine
• DL-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-
• O-(4-Hydroxy-3-iodophenyl)-3,5-diiodotyrosine
• Rathyronin
• Ratironina
• Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-
• rathyronine
• rac-Liothyronine-15N-13C9
• Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, DL- (8CI)
• 2-amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-diiodo-phenyl]propionic acid
• 2-azanyl-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-diiodo-phenyl]propanoic acid
• O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-DL-tyrosine

rac-Liothyronine-15N-13C9

CAS: 3130-96-9

Formula: C₆₁₃C₉H₁₂I₃₁₅NO₄

Color and Shape: White To Off-White Solid

Molecular weight: 660.90

Ref: 4Z-T-424