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CAS 3131-32-6

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Antazoline mesylate

Description:
Antazoline mesylate is a chemical compound that serves primarily as an antihistamine, often used in the treatment of allergic conditions and as a topical agent in ophthalmology. It is a salt formed from antazoline, a piperazine derivative, and methanesulfonic acid (mesylate). The compound exhibits properties typical of antihistamines, including the ability to block H1 histamine receptors, thereby alleviating symptoms associated with allergic reactions such as itching, redness, and swelling. Antazoline mesylate is characterized by its relatively low solubility in water, which can influence its formulation in pharmaceutical applications. It is typically administered in the form of eye drops or other topical preparations. The compound may also exhibit sedative effects, a common trait among first-generation antihistamines, due to its ability to cross the blood-brain barrier. Safety and efficacy profiles are well-documented, but like all medications, it may have side effects and contraindications that should be considered in clinical use.
Formula:C17H19N3·CH4O3S
InChI:InChI=1S/C17H19N3.CH4O3S/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;1-5(2,3)4/h1-10H,11-14H2,(H,18,19);1H3,(H,2,3,4)
InChI key:InChIKey=PIEHFGHAWYGNCY-UHFFFAOYSA-N
SMILES:N(CC1=CC=CC=C1)(CC=2NCCN2)C3=CC=CC=C3.S(C)(=O)(=O)O
Synonyms:
  • 1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-, methanesulfonate (1:1)
  • 1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-, monomethanesulfonate
  • 2-Imidazoline, 2-[(N-benzylanilino)methyl]-, monomethanesulfonate
  • 2-Phenylbenzylaminomethylimidazoline methanesulfonate
  • 2-{[benzyl(phenyl)amino]methyl}-4,5-dihydro-1H-imidazol-1-ium methanesulfonate
  • Analergin
  • Antazoline Mesylate
  • Antazoline methane sulphonate
  • Methanesulfonic acid, compd. with antazoline
  • NSC 7438
  • See more synonyms
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