CAS 313397-13-6

Reversan

Description:

Reversan, with the CAS number 313397-13-6, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential applications in reversing multidrug resistance in cancer therapy. It is classified as a small molecule and is known to interact with various biological targets, including certain transport proteins that are involved in drug efflux mechanisms. Reversan has been studied for its ability to enhance the efficacy of chemotherapeutic agents by inhibiting the activity of ATP-binding cassette (ABC) transporters, which are often overexpressed in resistant cancer cells. The compound exhibits a specific structure that contributes to its biological activity, and its pharmacological profile includes properties such as solubility and stability that are critical for therapeutic use. Research continues to explore its mechanisms of action, optimal dosing, and potential side effects, as well as its role in combination therapies aimed at improving treatment outcomes for patients with resistant tumors.

Formula: C₂₆H₂₇N₅O₂

Synonyms:

• CBLC4H10
• Reversan Q: What is the storage condition of
• N-[3-(4-morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
• Reversan Q: What is the CAS Number of
• Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-(4-morpholinyl)propyl]-5,7-diphenyl-
• Reversan
• Reversan Q: What are the applications of
• ReversanQ: What is
• 5,7-Diphenyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (3-morpholin-4-yl-propyl)-amide

Reversan

CAS: 313397-13-6

Formula: C₂₆H₂₇N₅O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 441.5249

Ref: IN-DA003U4D

N-(3-Morpholinopropyl)-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide

CAS: 313397-13-6

N-(3-Morpholinopropyl)-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide

Purity: 97%

Molecular weight: 441.54g/mol

Ref: 54-OR1068668

Reversan

CAS: 313397-13-6

Formula: C₂₆H₂₇N₅O₂

Molecular weight: 441.52

Ref: 7W-GL5958

Reversan

Controlled Product

CAS: 313397-13-6

Applications Reversan represents a new class of nontoxic MRP1 inhibitor, which may be clinically useful for the treatment of neuroblastoma.
References Sengupta, S., et al.: Pharmacol. Res., 42, 459 (2000), Norris, M., et al.: Med. Pediatr. Oncol., 36, 177 (2001), Haber, M., et al.: J. Clin. Oncol., 24, 1546 (2006), O'Connor, R., et al.: Cancer Chemother. Pharmacol., 59, 79 (2007),

Formula: C₂₆H₂₇N₅O₂

Color and Shape: Neat

Molecular weight: 441.52

Ref: TR-R279800

Reversan

CAS: 313397-13-6

Reversan(CBLC4H10) is a potent, nontoxic, and glioblastoma-associated inhibitor of multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (Pgp).

Formula: C₂₆H₂₇N₅O₂

Purity: 99.05%

Color and Shape: Solid

Molecular weight: 441.53

Ref: TM-T12714