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CAS 31356-86-2

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Uridine, 2'-deoxy-5-iodo-, 3',5'-bis(4-methylbenzoate)

Description:
Uridine, 2'-deoxy-5-iodo-, 3',5'-bis(4-methylbenzoate) is a modified nucleoside derivative characterized by the presence of a deoxyribose sugar, an iodine atom at the 5-position of the uracil base, and two esterified 4-methylbenzoate groups at the 3' and 5' positions. This compound is part of a class of nucleosides that can exhibit unique biochemical properties due to the modifications on the nucleobase and sugar moiety. The iodine substitution can influence the compound's reactivity and interaction with biological targets, potentially enhancing its stability or altering its binding affinity. The presence of the 4-methylbenzoate groups may also affect solubility and lipophilicity, which are important for cellular uptake and pharmacokinetics. Such modifications are often explored in medicinal chemistry for their potential applications in drug development, particularly in antiviral or anticancer therapies. Overall, this compound exemplifies the structural diversity found in nucleoside analogs, which can be tailored for specific biological functions.
Formula:C25H23IN2O7
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Found 2 products.
  • 2'-​Deoxy-​5-​iodouridine 3’,5’-bis(4-Methylbenzoate)
    TRC
    + Info

    2'-​Deoxy-​5-​iodouridine 3’,5’-bis(4-Methylbenzoate)

    Controlled Product
    CAS:
    Formula:C25H23IN2O7
    Color and Shape:Neat
    Molecular weight:590.364

    Ref: TR-D281530

    1g
    236.00€
    10g
    1,561.00€
  • 2'-Deoxy-5-iodo-3',5'-di-O-p-toluoyluridine
    Biosynth
    + Info

    2'-Deoxy-5-iodo-3',5'-di-O-p-toluoyluridine

    CAS:
    2'-Deoxy-5-iodo-3',5'-di-O-p-toluoyluridine is a nucleoside that has antiviral and anticancer effects. It can be used as an activator for phosphoramidites and as a precursor for the synthesis of other nucleosides. 2'-Deoxy-5-iodo-3',5'-di-O-p-toluoyluridine is synthesized from 2,4,6-triisopropylbenzenesulfonyl chloride and 5-(N,N-dimethylamino)valeronitrile in the presence of triethylamine and potassium carbonate in acetonitrile with subsequent purification by silica gel chromatography. The resulting compound is then converted to its diphosphate form by treatment with dithiothreitol in dimethylformamide. This product has been shown to inhibit DNA replication and
    Formula:C25H23IN2O7
    Purity:Min. 95%
    Molecular weight:590.36 g/mol

    Ref: 3D-ND138532

    1g
    403.00€
    500mg
    300.00€