CAS 31377-23-8

Amantadine sulfate

Description:

Amantadine sulfate is a chemical compound that serves primarily as an antiviral and antiparkinsonian agent. It is the sulfate salt of amantadine, which is a tricyclic amine. The compound is characterized by its ability to inhibit viral replication, particularly in the case of influenza A viruses, and is also used to manage symptoms of Parkinson's disease by enhancing dopaminergic activity in the brain. Amantadine sulfate is typically administered orally and is known for its relatively low toxicity profile. Physically, it appears as a white to off-white crystalline powder, and it is soluble in water, which facilitates its absorption in the body. The compound's mechanism of action involves blocking the M2 ion channel of the virus, thereby preventing uncoating and subsequent replication. Additionally, it may have effects on neurotransmitter release, contributing to its therapeutic effects in Parkinson's disease. As with any medication, potential side effects can include gastrointestinal disturbances, dizziness, and insomnia, necessitating careful monitoring during treatment.

Formula: C₁₀H₁₇NH₂O₄S

InChI: InChI=1S/C10H17N.H2O4S/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;1-5(2,3)4/h7-9H,1-6,11H2;(H2,1,2,3,4)

InChI key: InChIKey=PLRGINNCKYSSTP-UHFFFAOYSA-N

SMILES: S(=O)(=O)(O)O.NC12CC3CC(C1)CC(C2)C3

Synonyms:

• 1-Adamantanamine, sulfate (2:1)
• 1-Aminoadamantansulfate
• Amantadine Sulfate
• Amantadine Sulphate
• Infex
• PK-Merz
• Tricyclo[3.3.1.1^3,7]decan-1-amine, sulfate (2:1)
• Tricyclo[3.3.1.1~3,7~]Decan-1-Amine Sulfate
• Tricyclo[3.3.1.1~3,7~]Decan-1-Amine Sulfate (2:1)
• Tricyclo[3.3.1.13,7]decan-1-amine, sulfate (2:1)

1-Adamantanamine Sulfate

CAS: 31377-23-8

Formula: C₁₀H₁₇NH₂SO₄

Purity: >98.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 200.29

Ref: 3B-A1319

TRICYCLO[3.3.1.1(3,7)]DECAN-1-AMINE SULFATE

CAS: 31377-23-8

Formula: C₂₀H₃₆N₂O₄S

Purity: 96%

Color and Shape: Solid

Molecular weight: 400.5758

Ref: IN-DA003B0Y

1-Aminoadamantane sulphate

CAS: 31377-23-8

1-Aminoadamantane sulphate

Purity: 96%

Ref: 54-OR14312

Amantadine sulfate

CAS: 31377-23-8

Formula: C₁₀H₁₉NO₄S

Molecular weight: 249.33

Ref: 7W-GP6952

Amantadine sulfate (1-Adamantanamine Sulfate)

CAS: 31377-23-8

Formula: C₁₀H₁₇NH₂O₄S

Molecular weight: 151.25 1/2*98.07

Ref: 4Z-A-617

1-Adamantanamine Sulfate

CAS: 31377-23-8

Stability Hygroscopic
Applications 1-Adamantanamine Sulfate (cas# 31377-23-8) is a useful research chemical.

Formula: (C₁₀H₁₇N)·H₂SO₄

Color and Shape: Neat

Molecular weight: 2(151.25) + 98.08

Ref: TR-A576010

Amantadine sulfate

CAS: 31377-23-8

Amantadine: antiviral, anti-Parkinson's, blocks NMDA receptors, boosts dopamine/norepinephrine release.

Formula: C₂₀H₃₆N₂O₄S

Color and Shape: White Fine Crystalline Powder

Molecular weight: 400.58

Ref: TM-T1406L

Adamantan-1-amine sulfate

CAS: 31377-23-8

Formula: C₁₀H₁₉NO₄S

Purity: 96%+;RG

Molecular weight: 249.33

Ref: 10-F324770

1-Aminoadamantane sulphate

Controlled Product

CAS: 31377-23-8

1-Aminoadamantane sulphate is a drug that has been used for the treatment of autoimmune diseases, such as multiple sclerosis and chronic inflammatory demyelinating polyneuropathy. It inhibits Na channels in nerves and therefore blocks the transmission of nerve impulses. 1-Aminoadamantane sulphate has also shown to inhibit amyloid protein formation, which is associated with Alzheimer's disease. This drug binds to an adenine nucleotide and inhibits the transport of hydrogen fluoride into cells. The drug also has anti-viral properties. 1-Aminoadamantane sulphate is able to bind to calcium ions and prevent the binding of viruses to cells by interfering with their ability to attach themselves to the cell surface.

Color and Shape: White Off-White Powder

Molecular weight: 400.58 g/mol

Ref: 3D-FA00423