CAS 31377-23-8: Amantadine sulfate
Description:Amantadine sulfate is a chemical compound that serves primarily as an antiviral and antiparkinsonian agent. It is the sulfate salt of amantadine, which is a tricyclic amine. The compound is characterized by its ability to inhibit viral replication, particularly in the case of influenza A viruses, and is also used to manage symptoms of Parkinson's disease by enhancing dopaminergic activity in the brain. Amantadine sulfate is typically administered orally and is known for its relatively low toxicity profile. Physically, it appears as a white to off-white crystalline powder, and it is soluble in water, which facilitates its absorption in the body. The compound's mechanism of action involves blocking the M2 ion channel of the virus, thereby preventing uncoating and subsequent replication. Additionally, it may have effects on neurotransmitter release, contributing to its therapeutic effects in Parkinson's disease. As with any medication, potential side effects can include gastrointestinal disturbances, dizziness, and insomnia, necessitating careful monitoring during treatment.
Formula:C10H17NH2O4S
InChI:InChI=1S/C10H17N.H2O4S/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;1-5(2,3)4/h7-9H,1-6,11H2;(H2,1,2,3,4)
InChI key:InChIKey=PLRGINNCKYSSTP-UHFFFAOYSA-N
SMILES:O=S(=O)(O)O.NC12CC3CC(CC(C3)C1)C2
- Synonyms:
- 1-Adamantanamine, sulfate (2:1)
- 1-Aminoadamantansulfate
- Amantadine Sulfate
- Amantadine Sulphate
- Infex
- PK-Merz
- Tricyclo[3.3.1.1<sup>3,7</sup>]decan-1-amine, sulfate (2:1)
- Tricyclo[3.3.1.1~3,7~]Decan-1-Amine Sulfate
- Tricyclo[3.3.1.1~3,7~]Decan-1-Amine Sulfate (2:1)
- Tricyclo[3.3.1.13,7]decan-1-amine, sulfate (2:1)
- See more synonyms
