CAS 314-13-6

Evan's Blue

Description:

Evan's Blue, with the CAS number 314-13-6, is a synthetic dye belonging to the class of azo dyes. It is characterized by its deep blue color and is primarily used as a biological stain and a tracer in various scientific applications. The compound has a molecular formula that includes both nitrogen and sulfur, contributing to its stability and solubility in water. Evan's Blue is known for its ability to bind to serum albumin, making it useful in studies related to vascular permeability and blood volume measurement. Additionally, it has applications in histology and microscopy for staining tissues. The dye is generally considered safe for laboratory use, although precautions should be taken to avoid ingestion or prolonged skin contact. Its unique properties make it valuable in both research and clinical settings, particularly in studies involving the circulatory system and tissue analysis.

Formula: C₃₄H₂₈N₆O₁₄S₄·4Na

InChI: InChI=1S/C34H28N6O14S4.4Na/c1-15-11-17(3-7-21(15)37-39-23-9-5-19-25(55(43,44)45)13-27(57(49,50)51)31(35)29(19)33(23)41)18-4-8-22(16(2)12-18)38-40-24-10-6-20-26(56(46,47)48)14-28(58(52,53)54)32(36)30(20)34(24)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;

InChI key: InChIKey=WWWSEHAFEUPVKD-UHFFFAOYSA-N

SMILES: NC=1C2=C(C(S(=O)(=O)O)=CC1S(=O)(=O)O)C=CC(N=NC3=C(C)C=C(C=C3)C4=CC(C)=C(N=NC5=C(O)C6=C(C=C5)C(S(=O)(=O)O)=CC(S(=O)(=O)O)=C6N)C=C4)=C2O.[Na]

Synonyms:

• 1,3-Naphthalenedisulfonic acid, 6,6′-[(3,3′-dimethyl[1,1′-biphenyl]-4,4′-diyl)bis(2,1-diazenediyl)]bis[4-amino-5-hydroxy-, sodium salt (1:4)
• 1,3-Naphthalenedisulfonic acid, 6,6′-[(3,3′-dimethyl[1,1′-biphenyl]-4,4′-diyl)bis(azo)]bis[4-amino-5-hydroxy-, tetrasodium salt
• 4,4′-Bis[7-(1-amino-8-hydroxy-2,4-disulfo)naphthylazo]-3,3′-bitolyl tetrasodium salt
• Azovan Blue
• Diazol Pure Blue BF
• Direct Blue 53
• Evan's Blue
• Evans Blue Fluka
• Evens Blue
• T 1824
• Tetrasodium 6,6-((3,3-Dimethyl-(1,1-Biphenyl-4,4Diyl)Bis(Azo)Bis(4-Amino-5-Hydroxy-1,3-Naphthalenedisulphonate)
• blue Evan
• tetrasodium (6E,6'E)-6,6'-[(3,3'-dimethylbiphenyl-4,4'-diyl)di(1E)hydrazin-2-yl-1-ylidene]bis(4-amino-5-oxo-5,6-dihydronaphthalene-1,3-disulfonate)
• tetrasodium (6Z)-4-amino-6-({4'-[(2E)-2-(8-amino-1-oxo-5,7-disulfonatonaphthalen-2(1H)-ylidene)hydrazino]-3,3'-dimethylbiphenyl-4-yl}hydrazono)-5-oxo-5,6-dihydronaphthalene-1,3-disulfonate
• tetrasodium 6,6'-[(3,3'-dimethylbiphenyl-4,4'-diyl)di(E)diazene-2,1-diyl]bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate)
• C.I. Direct Blue 53, tetrasodium salt
• evans blue (C.I. 23860)
• C.I. Direct Blue 53
• C.I. Direct Blue 53, tetrasodium salt (8CI)
• C.I. direct blue 53 tetrasodium salt
• Evans blue

Evans Blue

CAS: 314-13-6

Formula: C₃₄H₂₄N₆Na₄O₁₄S₄

Purity: >80.0%(HPLC)

Color and Shape: Amber to Dark green to Black powder to crystal

Molecular weight: 960.79

Ref: 3B-E0197

Evans Blue

CAS: 314-13-6

Evans Blue is used for estimation of blood volume and in double-labeling procedure for studying axonal branching. It acts as an inhibitor of L-glutamate and kainate receptor-mediated currents. It is also a P2X-selective purinoceptor antagonist. It is also useful in molecular biology. This Thermo Sc

Formula: C₃₄H₂₄N₆Na₄O₁₄S₄

Color and Shape: Powder and/or Crystals, Dark brown to dark red to purple

Molecular weight: 960.79

Ref: 02-A16774

Evans blue

CAS: 314-13-6

Evans blue (C.I. 23860) is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT).

Formula: C₃₄H₂₄N₆Na₄O₁₄S₄

Purity: 86.41% - 97.13%

Color and Shape: Dark Brown

Molecular weight: 960.78

Ref: TM-T0313

Evans Blue

CAS: 314-13-6

Evans Blue

Purity: 87%

Color and Shape: Dark Brown Powder

Molecular weight: 960.81g/mol

Ref: 54-BIE0601

Evans Blue (C.I. 23860)

CAS: 314-13-6

Formula: C₃₄H₂₄N₆Na₄O₁₄S₄

Color and Shape: Dark red-brown, dark purple or black powder

Molecular weight: 960.82

Ref: 7W-GT1064

Evans blue

CAS: 314-13-6

Evans blue

Purity: ≥80%

Molecular weight: 960.78g/mol

Ref: 54-BUP14871

Evans blue (Technical Grade)

Controlled Product

CAS: 314-13-6

Stability Hygroscopic, Light Sensitive
Applications Evans blue Dyes and metabolites

Formula: C₃₄H₂₄N₆Na₄O₁₄S₄

Color and Shape: Neat

Molecular weight: 960.81

Ref: TR-E945203

Evans Blue

CAS: 314-13-6

Formula: C₃₄H₂₄N₆O₁₄S₄Na₄

Color and Shape: Dark brown to black, Powder to crystals to granules

Molecular weight: 960.81

Ref: SR-46650

Evans blue

CAS: 314-13-6

Evans blue is a basic protein that binds to the active site of metalloproteinases, such as MMP-9. It is used in the study of enzyme activities and in biological samples for determining levels of MMP-9 activity. Caproic acid is capable of chelating metal ions and is often used as a substrate for measuring water permeability. Evans blue has been shown to have a hypoglycemic effect and can be used as a pharmacological agent for treating conditions such as ischemia-reperfusion injury, congestive heart failure, and toll-like receptor 4 (TLR4) mediated inflammation.

Formula: C₃₄H₂₄N₆O₁₄S₄Na₄

Purity: Min. 95%

Molecular weight: 960.81 g/mol

Ref: 3D-FE47135