CAS 314-19-2

(-)-Apomorphine hydrochloride

Description:

(-)-Apomorphine hydrochloride is a chemical compound that serves as a potent dopamine agonist, primarily used in the treatment of Parkinson's disease and erectile dysfunction. It is derived from morphine and is characterized by its ability to stimulate dopamine receptors in the brain, which can help alleviate motor symptoms associated with Parkinson's. The hydrochloride salt form enhances its solubility in water, making it suitable for injection or sublingual administration. The compound is typically a white to off-white crystalline powder and is known for its relatively low oral bioavailability. Its pharmacological effects include inducing emesis (vomiting) at higher doses, which is a notable side effect. (-)-Apomorphine hydrochloride has a specific stereochemistry that contributes to its biological activity, and it is important to handle it with care due to its potent effects on the central nervous system. As with any medication, it is essential to consider potential interactions and contraindications when prescribing or using this compound.

Formula: C₁₇H₁₇NO₂·ClH

InChI: InChI=1S/C17H17NO2.ClH/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12;/h2-6,13,19-20H,7-9H2,1H3;1H/t13-;/m1./s1

InChI key: InChIKey=SKYZYDSNJIOXRL-BTQNPOSSSA-N

SMILES: CN1[C@]2(C=3C(C=4C(C2)=CC=C(O)C4O)=CC=CC3CC1)[H].Cl

Synonyms:

• (-)-Apomorphinium hydrochloride
• (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo(de,g)chinolin-10,11-diol hydrochlorid
• (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride (1:1)
• (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride
• 4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aR)-
• 4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, (6aR)-
• 4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, (R)-
• 5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo(de,g)chinolin-10,11-diol hydrochlorid
• 6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride
• 6a-beta-Aporphine-10,11-diol, hydrochloride
• 6a-beta-Noraporphine-10,11-diol, 6-methyl-, hydrochloride
• 6abeta-Aporphine-10,11-diol, hydrochloride (8CI)
• 6abeta-Noraporphine-10,11-diol, 6-methyl-, hydrochloride
• 6aβ-Aporphine-10,11-diol, hydrochloride
• Apokyn
• Apomorfina, Clorhidrato
• Apomorphin hydrochlorid
• Apomorphine HCl
• Apomorphine SL
• Apomorphine chloride
• Apomorphine hydrochloride anhydrous
• Apomorphine, chlorhydrate
• Apomorphinhydrochlorid
• Apomorphinium chloride
• Apomorphinum hydrochloricum
• Ixense
• N-Methylnorapomorphine hydrochloride
• Nsc 11442
• Pomorphini Hydrochloridum
• R-(-)-Apomorphine hydrochloride
• Taluvian
• Unii-9K13Md7A0D
• Unii-F39049Y068
• Uprima
• Apomorphine hydrochloride

Apomorphine.HCl

CAS: 314-19-2

Color and Shape: Neat

Ref: LP-M-213-HC-10

Apomorphine HCl

CAS: 314-19-2

Formula: C₁₇H₁₇NO₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 267.33 36.46

Ref: 4Z-A-208001

Apomorphine-13C-d3 HCl

CAS: 314-19-2

Formula: C₁₆₁₃CH₁₄D₃NO₂·HCl

Color and Shape: Off-White Solid

Molecular weight: 271.34 36.46

Ref: 4Z-A-208003

Apomorphine.HCl, 1mg/ml in Methanol (as free base)

CAS: 314-19-2

Color and Shape: Single Solution

Ref: LP-M-213-HC-1LM

(R)-Apomorphine-d5 Hydrochloride (Major)

Controlled Product

CAS: 314-19-2, 58-00-4, 76787-62-7

Formula: C₁₇H₁₂D₅NO₂•HCl

Color and Shape: Neat

Molecular weight: 272.363646

Ref: TR-A727503

(R)-Apomorphine hydrochloride

CAS: 314-19-2

Apomorphine hydrochloride is the salt form of apomorphine, a morphine derivative D2 dopamine agonist. The high selectivity for D2, D3, D4 and D5 receptors makes apomorphine hydrochloride a possible drug candidate and is in clinical trials for the diagnosis and treatment of Parkinson’s disease. Moreover, apomorphine and apomorphine hydrochloride have been investigated in diverse studies for treating movement disorders.

Formula: C₁₇H₁₇NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 267.32 g/mol

Ref: 3D-FA31759