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CAS 314-19-2

:

(-)-Apomorphine hydrochloride

Description:
(-)-Apomorphine hydrochloride is a chemical compound that serves as a potent dopamine agonist, primarily used in the treatment of Parkinson's disease and erectile dysfunction. It is derived from morphine and is characterized by its ability to stimulate dopamine receptors in the brain, which can help alleviate motor symptoms associated with Parkinson's. The hydrochloride salt form enhances its solubility in water, making it suitable for injection or sublingual administration. The compound is typically a white to off-white crystalline powder and is known for its relatively low oral bioavailability. Its pharmacological effects include inducing emesis (vomiting) at higher doses, which is a notable side effect. (-)-Apomorphine hydrochloride has a specific stereochemistry that contributes to its biological activity, and it is important to handle it with care due to its potent effects on the central nervous system. As with any medication, it is essential to consider potential interactions and contraindications when prescribing or using this compound.
Formula:C17H17NO2·ClH
InChI:InChI=1S/C17H17NO2.ClH/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12;/h2-6,13,19-20H,7-9H2,1H3;1H/t13-;/m1./s1
InChI key:InChIKey=SKYZYDSNJIOXRL-BTQNPOSSSA-N
SMILES:CN1[C@]2(C=3C(C=4C(C2)=CC=C(O)C4O)=CC=CC3CC1)[H].Cl
Synonyms:
  • (-)-Apomorphinium hydrochloride
  • (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo(de,g)chinolin-10,11-diol hydrochlorid
  • (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride (1:1)
  • (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride
  • 4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aR)-
  • 4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, (6aR)-
  • 4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, (R)-
  • 5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo(de,g)chinolin-10,11-diol hydrochlorid
  • 6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride
  • 6a-beta-Aporphine-10,11-diol, hydrochloride
  • See more synonyms
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Found 5 products.