CAS 314045-39-1

bis-2-(5-Phenylacetmido-1,2,4-Thiadiazol-2-yl)Ethyl Sulfide

Description:

Bis-2-(5-Phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide is a chemical compound characterized by its unique structure, which includes a thiadiazole ring and an ethyl sulfide moiety. This compound typically exhibits properties associated with both the thiadiazole and sulfide functional groups, such as potential biological activity and solubility in organic solvents. The presence of the phenylacetamido group suggests that it may have applications in medicinal chemistry, possibly as an antimicrobial or anti-inflammatory agent. The compound's molecular structure may contribute to its reactivity and interaction with biological targets. Additionally, its synthesis and stability under various conditions are important for its practical applications. As with many thiadiazole derivatives, it may also exhibit interesting electronic properties, making it a candidate for further research in fields such as materials science or pharmacology. However, specific characteristics such as melting point, boiling point, and solubility would require empirical data for precise evaluation.

BIS-2-(5-PHENYLACETAMIDO-1,3,4-THIADIAZOL-2-YL)ETHYL SULFIDE

CAS: 314045-39-1

Formula: C₂₄H₂₄N₆O₂S₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 524.6814

Ref: IN-DA003ODK

BPTES

CAS: 314045-39-1

BPTES

Purity: ≥95%

Molecular weight: 524.68g/mol

Ref: 54-BUP15216

BPTES

CAS: 314045-39-1

BPTES(IC50 of 0.16 μM) is an effective and specific GlutamiN/Ase GLS1 (KGA) inhibitor.

Formula: C₂₄H₂₄N₆O₂S₃

Purity: 95.83% - 99.64%

Color and Shape: Solid

Molecular weight: 524.68

Ref: TM-T6791

BPTES

CAS: 314045-39-1

BPTES

Purity: 98%

Molecular weight: 524.68g/mol

Ref: 54-BISN0095

BPTES

CAS: 314045-39-1

Ref: 7W-GW0930

BPTES-d10

Controlled Product

CAS: 314045-39-1

Applications BPTES-d10 is the isotope labelled analog of BPTES (B676675); a potent and selective glutaminase inhibitor. Used in the treatment of renal cell carcinomas resulting from overexpression of the MYC oncogene.
References Shroff, E. et al.: PNAS. U.S.A., 112, 6539 (2015); Thomas, A. et al.: Biochem. Biophys. Res. Comm., 443, 32 (2014)

Formula: C₂₄D₁₀H₁₄N₆O₂S₃

Color and Shape: Neat

Molecular weight: 534.743

Ref: TR-B676677

BPTES

Controlled Product

CAS: 314045-39-1

Applications BPTES is a potent and selective Glutaminase inhibitor. Used in the treatment of renal cell carcinomas resulting from overexpression of the MYC oncogene.
References Shroff, E. et al.: PNAS. U.S.A., 112, 6539 (2015); Thomas, A. et al.: Biochem. Biophys. Res. Comm., 443, 32 (2014);

Formula: C₂₄H₂₄N₆O₂S₃

Color and Shape: Neat

Molecular weight: 524.68

Ref: TR-B676675

Glutaminase Inhibitor II, BPTES

CAS: 314045-39-1

The Glutaminase Inhibitor II, BPTES is a glutaminase inhibitor that is used to treat cancer. It binds to the active site of glutaminase and inhibits the enzyme from catalyzing the conversion of glutamine to glutamate. This results in reduced production of ATP, which leads to cell death. The minimal toxicity of this drug has been shown in animal models using a dinucleotide phosphate-based assay. BPTES has also been shown to inhibit mitochondrial membrane potential and induce apoptosis by decreasing levels of reactive oxygen species (ROS) and increasing mitochondrial membrane potential in a model system. BPTES can also synergize with other drugs such as anticancer agents or radiation therapy, resulting in increased efficacy against tumor cells.

Formula: C₂₄H₂₄N₆O₂S₃

Purity: Min. 95%

Molecular weight: 524.68 g/mol

Ref: 3D-PMA04539