CAS 31431-43-3

Cyclobendazole

Description:

Cyclobendazole is a benzimidazole derivative primarily known for its use as an anthelmintic agent in veterinary medicine. It exhibits a broad-spectrum activity against various parasitic worms, making it effective in treating infections in livestock and pets. The chemical structure of cyclobendazole features a bicyclic system that contributes to its pharmacological properties. It is typically characterized by its low solubility in water, which influences its bioavailability and absorption in biological systems. Cyclobendazole acts by inhibiting the polymerization of tubulin, disrupting the microtubule formation necessary for cellular processes in parasites. This mechanism of action is similar to other benzimidazole compounds, leading to the eventual death of the parasite. Additionally, cyclobendazole has a relatively low toxicity profile in target animals, making it a preferred choice in veterinary applications. However, as with any pharmaceutical, proper dosage and administration are crucial to minimize potential side effects and ensure efficacy. Its environmental impact and residue management in food-producing animals are also important considerations in its use.

Formula: C₁₃H₁₃N₃O₃

InChI: InChI=1S/C13H13N3O3/c1-19-13(18)16-12-14-9-5-4-8(6-10(9)15-12)11(17)7-2-3-7/h4-7H,2-3H2,1H3,(H2,14,15,16,18)

InChI key: InChIKey=OXLKOMYHDYVIDM-UHFFFAOYSA-N

SMILES: C(=O)(C=1C=C2C(N=C(NC(OC)=O)N2)=CC1)C3CC3

Synonyms:

• 2-Benzimidazolecarbamic acid, 5-(cyclopropylcarbonyl)-, methyl ester
• 5-(Cyclopropylcarbonyl)-2-benzimidazolecarbamic acid methyl ester
• 5-Cyclopropylcarbonylcarbendazime
• Brn 0755755
• Carbamic acid, (5-(cyclopropylcarbonyl)-1H-benzimidazol-2-yl)-, methyl ester
• Carbamic acid, N-[6-(cyclopropylcarbonyl)-1H-benzimidazol-2-yl]-, methyl ester
• Cc 2481
• Ciclobendazol
• Ciclobendazol [INN-Spanish]
• Ciclobendazolum
• Ciclobendazolum [INN-Latin]
• Cyclobendazole
• Cyclobendazole [USAN]
• Haptocil
• Methyl 5-(cyclopropylcarbonyl)-2-benzimidazolecarbamate
• Nsc 335307
• R 17,147
• Unii-Jf3Kq40J31
• methyl [6-(cyclopropylcarbonyl)-1H-benzimidazol-2-yl]carbamate

Cyclobendazole

CAS: 31431-43-3

Cyclobendazole is a antihelmintic agent.

Formula: C₁₃H₁₃N₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 259.26

Ref: TM-T23922

Cyclobendazole

CAS: 31431-43-3

Cyclobendazole is a benzimidazole derivative that is used as an anthelmintic drug. It enters the worm's body and prevents the synthesis of ergosterol, which is a component of the cell membrane that protects the cell from harmful substances. Cyclobendazole disrupts the hydrogen bonds by forming new covalent bonds with the DNA bases, leading to programmed death in parasites and worms. This drug has been shown to be effective against inflammatory bowel disease and cancer in clinical studies. Cyclobendazole has also been shown to have anti-inflammatory activity in animal models for inflammatory bowel disease, colitis, and rheumatoid arthritis.

Formula: C₁₃H₁₃N₃O₃

Purity: Min. 95%

Molecular weight: 259.26 g/mol

Ref: 3D-GBA43143